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Publication Name World Journal of Gastroenterology
Manuscript ID 20235
Country/Territory Taiwan
2015-05-30 12:26
Peer-Review Started
2015-06-04 08:50
To Make the First Decision
2015-07-14 11:50
Return for Revision
2015-07-27 19:10
2015-08-14 13:09
Second Decision
2015-10-14 09:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-26 17:52
Articles in Press
2015-10-26 17:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-01-05 19:38
Publish the Manuscript Online
2016-01-20 16:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Metabolic alterations and hepatitis C: From bench to bedside
Manuscript Source Invited Manuscript
All Author List Ming-Ling Chang
Funding Agency and Grant Number
Funding Agency Grant Number
Chang Gung Medical Research Program CMRPG380353
Chang Gung Medical Research Program CMRPG3B1251
Chang Gung Medical Research Program CMRPG3B0401
Chang Gung Medical Research Program CMRPG3B1741
Chang Gung Medical Research Program CMRPG3B1742
Chang Gung Medical Research Program XMRPG3A0521
National Science Council, Taiwan 100-2314-B-182-069-
National Science Council, Taiwan 101-2314-B-182-083-
National Science Council, Taiwan 102-2628-B-182-021-MY3
Corresponding author Ming-Ling Chang, MD, PhD, Liver Research Center, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, No. 5, Fu Hsing Street, Kuei Shan, Taoyuan 33305, Taiwan. mlchang8210@gmail.com
Keywords Lipid; Glucose; Cardiovascular; Hepatitis C virus; Core; Nonstructural protein 5 A; Transgenic mice
Core Tip Hepatitis C virus (HCV) is thought to cause hypolipidemia, hepatic steatosis, insulin resistance, and diabetes. Its life cycle depends on host cholesterol metabolism. HCV core protein and nonstructural protein 5A perturb crucial metabolic pathways. Many cross-sectional studies have demonstrated increased cardiometabolic risks in HCV patients. Utilizing anti-HCV therapy, most cohort studies have demonstrated the favorable effects of HCV clearance in attenuating cardiometabolic risks. Adipose tissue is an important endocrine organ due to its release of adipocytokines, which strongly regulate metabolism. A comprehensive overview of HCV-associated metabolic and adipocyto-kine alterations, from bench to bedside, is presented in this topic highlight.
Publish Date 2016-01-20 16:55
Citation Chang ML. Metabolic alterations and hepatitis C: From bench to bedside. World J Gastroenterol 2016; 22(4): 1461-1476
Url http://www.wjgnet.com/1007-9327/full/v22/i4/1461.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i4.1461
Full Article (PDF) WJG-22-1461.pdf
Full Article (Word) WJG-22-1461.doc
Manuscript File 20235-Review.doc
Answering Reviewers 20235-Answering reviewers.pdf
Audio Core Tip 20235-Audio core tip.mp3
Copyright License Agreement 20235-Copyright assignment.pdf
Peer-review Report 20235-Peer-review(s).pdf
Scientific Misconduct Check 20235-Scientific misconduct check.pdf
Scientific Editor Work List 20235-Scientific editor work list.pdf