Publication Name	World Journal of Gastroenterology
Manuscript ID	20247
Country	Italy

Received	2015-05-30 14:27
Peer-Review Started	2015-06-04 15:08
To Make the First Decision	2015-10-14 17:02
Return for Revision	2015-10-15 14:04
Revised	2015-11-23 07:14
Second Decision	2015-12-18 16:05
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-30 17:42
Articles in Press	2015-12-30 17:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-15 18:42
Publish the Manuscript Online	2016-01-23 17:08

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Critical Care Medicine
Manuscript Type	Topic Highlights
Article Title	Coagulopathy and transfusion therapy in pediatric liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Mirco Nacoti, Davide Corbella, Francesco Fazzi, Francesca Rapido and Ezio Bonanomi
Funding Agency and Grant Number
Corresponding Author	Mirco Nacoti, MD, Pediatric Intensive Care Unit, Ospedale Papa Giovanni XXIII Piazza OMS, Organizzazione Mondiale della Sanità 1, 24127 Bergamo, Italy. mnacoti@hpg23.it
Key Words	Children; Coagulation; Thrombosis; Liver disease; Transfusion; Transplantation; Point of care coagulation
Core Tip	In the last two decades, extensive investigation of abnormalities in hemostasis in adult cirrhotic patients and improvements in both surgical and anesthetic management has enhanced outcome following liver transplantation. Unfortunately, such knowledge cannot be directly applied to pediatric patients, as major differences exist between adults and children undergoing liver transplantation. In this review, we discuss the pattern of hemostatic abnormalities in children with end-stage liver disease, point-of-care coagulation monitoring, and clinical strategies designed to reduce bleeding and thrombosis in pediatric liver transplantation. In conclusion, we propose a prioritized research agenda for this pediatric subspecialty.
Publish Date	2016-01-23 17:08
Citation	Nacoti M, Corbella D, Fazzi F, Rapido F, Bonanomi E. Coagulopathy and transfusion therapy in pediatric liver transplantation. World J Gastroenterol 2016; 22(6): 2005-2023
URL	http://www.wjgnet.com/1007-9327/full/v22/i6/2005.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i6.2005

Full Article (PDF)	WJG-22-2005.pdf
Full Article (Word)	WJG-22-2005.doc
Manuscript File	20247-Review.docx
Answering Reviewers	20247-Answering reviewers.pdf
Audio Core Tip	20247-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20247-Conflict-of-interest statement.pdf
Copyright License Agreement	20247-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20247-Language certificate.pdf
Supplementary Material	Supplementary_Material_20150530005448.pdf
Peer-review Report	20247-Peer-review(s).pdf
Scientific Misconduct Check	20247-Scientific misconduct check.pdf
Scientific Editor Work List	20247-Scientific editor work list.pdf