Publication Name	World Journal of Critical Care Medicine
Manuscript ID	20259
Country	Brazil

Received	2015-05-30 14:53
Peer-Review Started	2015-05-30 16:18
To Make the First Decision	2015-08-14 15:24
Return for Revision	2015-08-22 17:25
Revised	2015-09-08 20:03
Second Decision	2015-10-13 08:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-27 17:59
Articles in Press	2015-10-27 17:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-29 10:57
Publish the Manuscript Online	2015-11-06 18:44

ISSN	2220-3141(online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way
Manuscript Source	Invited Manuscript
All Author List	Raquel S Santos, Pedro L Silva, Paolo Pelosi and Patricia RM Rocco
Funding Agency and Grant Number	Funding Agency Grant Number Brazilian Council for Scientific and Technological Development (CNPq) Carlos Chagas Filho Rio de Janeiro State Research Foundation (FAPERJ) Department of Science and Technology (DECIT)/Brazilian Ministry of Health Coordination for the Improvement of Higher Level Personnel (CAPES)
Corresponding Author	Patricia RM Rocco, MD, PhD, Professor, Laboratory of Pulmonary Investigation, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Centro de Ciências da Saúde, Avenida Carlos Chagas Filho, s/n, Bloco G-014, Ilha do Fundão, Rio de Janeiro 21941-902, Brazil. prmrocco@gmail.com
Key Words	Recruitment maneuvers; Acute respiratory distress syndrome; Positive end-expiratory pressure; Transpulmonary pressure; Lung ultrasonography
Core Tip	Experimental and clinical studies show that stepwise recruitment maneuvers (RMs) improve oxy-genation and lung aeration and are associated with less hemo-dynamic instability and inflammatory impact on lung tissue compared to traditional abrupt maneuvers. Patients with severe acute respiratory distress syndrome, characterized by increased edema and atelectasis, are good candidates for RMs. Patients whose oxygenation improves with increased pressure are at lower risk of death. Post-recruitment positive end-expiratory pressure (PEEP) titration is critical to maintaining stabilization of alveolar units and avoiding derecruitment. The use of individualized PEEP based on lung compliance might move clinical management forward.
Publish Date	2015-11-06 18:44
Citation	Santos RS, Silva PL, Pelosi P, Rocco PRM. Recruitment maneuvers in acute respiratory distress syndrome: The safe way is the best way. World J Crit Care Med 2015; 4(4): 278-286
URL	http://www.wjgnet.com/2220-3141/full/v4/i4/278.htm
DOI	http://dx.doi.org/10.5492/wjccm.v4.i4.278

Full Article (PDF)	WJCCM-4-278.pdf
Full Article (Word)	WJCCM-4-278.doc
Manuscript File	20259-Review.doc
Answering Reviewers	20259-Answering reviewers.pdf
Audio Core Tip	20259-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	20259-Conflict-of-interest statement.pdf
Copyright License Agreement	20259-Copyright assignment.pdf
Peer-review Report	20259-Peer-review(s).pdf
Scientific Misconduct Check	20259-Scientific misconduct check.pdf
Scientific Editor Work List	20259-Scientific editor work list.pdf