Publication Name	World Journal of Gastroenterology
Manuscript ID	2026
Country	China

Received	2013-01-21 14:54
Peer-Review Started	2013-01-21 15:09
To Make the First Decision	2013-03-25 15:20
Return for Revision	2013-04-07 10:06
Revised	2013-04-25 17:05
Second Decision	2013-06-03 15:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-06-04 09:07
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-06-28 10:41
Typeset the Manuscript	2013-07-12 14:02
Publish the Manuscript Online	2013-07-29 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Basic transcription factor 3 is involved in gastric cancer development and progression
Manuscript Source	Invited Manuscript
All Author List	Qi Liu, Jian-Ping Zhou, Bin Li, Zhong-Cheng Huang, Hong-Yu Dong, Guang-Yi Li, Ke Zhou and Shao-Lin Nie
Funding Agency and Grant Number	Funding Agency Grant Number Science and Technology Project of Hunan Province, China 2013FJ3151
Corresponding Author	Shao-Lin Nie, MD, Professor of Medicine, Deputy Chief, Department of Gastrointestinal Surgery, Hunan Provincial Tumor Hospital, the Affiliated Tumor Hospital of Central South University, No. 582 Xianjia Lake Road, Changsha 410013, Hunan Province, China. nieslbm@163.com
Key Words	Basic transcription factor 3; Gastric cancer; Small interfering RNA; Proliferation; Apoptosis; Cell cycle
Core Tip	After we found that basic transcription factor 3 (BTF3) transcription rates in human gastric tumor tissue samples were significantly higher than in adjacent normal tissues, we extended our study on gastric cancer cell lines. We silenced BTF3 in SGC7901 cells, which led to 82%, 70%, 57%, 49% and 44% proliferation rates of the control within the first 5 d after infection with a small interfering RNA-BTF3 containing lentivirus. After BTF3 silencing, the percentage the G1 phase arrested SGC7901 cells was decreased (P = 0.000), the percentages of cells in the S (P = 0.031) and G2/M (P = 0.027) phases were increased and the apoptosis rate increased from 5.73% to 8.59% (P = 0.014).
Publish Date	2013-07-29 11:18
Citation	Liu Q, Zhou JP, Li B, Huang ZC, Dong HY, Li GY, Zhou K, Nie SL. Basic transcription factor 3 is involved in gastric cancer development and progression. World J Gastroenterol 2013; 19(28): 4495-4503
URL	http://www.wjgnet.com/1007-9327/full/v19/i28/4495.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i28.4495

Full Article (PDF)	WJG-19-4495.pdf
Manuscript File	2026-Review.doc
Answering Reviewers	2026-Answering reviewers.pdf
Copyright License Agreement	2026-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2026-Language certificate.pdf
Peer-review Report	2026-Peer review.pdf
Scientific Editor Work List	2026-Scientific editor work list.doc