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11/27/2015 2:08:00 PM | Browse: 938 | Download: 1318
Publication Name World Journal of Gastroenterology
Manuscript ID 20319
Country United States
Received
2015-06-01 17:57
Peer-Review Started
2015-06-02 19:48
To Make the First Decision
2015-06-19 17:45
Return for Revision
2015-06-24 15:40
Revised
2015-07-13 22:06
Second Decision
2015-08-19 15:06
Accepted by Journal Editor-in-Chief
2015-08-19 16:44
Accepted by Company Editor-in-Chief
2015-08-31 18:01
Articles in Press
2015-08-31 18:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-11-15 18:08
Publish the Manuscript Online
2015-11-27 14:01
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Report
Article Title Characteristic clinical features of Aspergillus appendicitis: Case report and literature review
Manuscript Source Unsolicited Manuscript
All Author List Mihajlo Gjeorgjievski, Mitual B Amin and Mitchell S Cappell
Funding Agency and Grant Number
Corresponding Author Mitchell S Cappell, MD, PhD, Chief, Division of Gastroenterology and Hepatology, William Beaumont Hospital, MOB #602, 3535 West Thirteen Mile Road, Royal Oak, Mi 48073, United States. mscappell@yahoo.com
Key Words Aspergillosis; Aspergillus appendicitis; Fungal appendicitis; Appendicitis; Neutropenia; Chemotherapy; Acute myelocytic leukemia
Core Tip This work reports the fourth reported case of isolated Aspergillus appendicitis, further characterizes this syndrome, and identifies a clinical pentad associated with this syndrome: clinically-suspected appendicitis, neutropenia, recent chemotherapy, acute leukemia, and poor clinical course if treated solely with antibacterial or anti-Candidial antibiotics. These risk factors are biologically reasonable. Immunosuppression from neutropenia and acute leukemia may promote Aspergillus appendicitis. Local gastrointestinal ulcers from recent chemotherapy provides a nidus for fungal colonization. In patients presenting with this proposed pentad, Aspergillus appendicitis should be considered in the differential diagnosis, special silver stains should be performed to evaluate for this infection, and empiric anti-Aspergillus therapy may be considered pending tissue diagnosis.
Publish Date 2015-11-27 14:01
Citation Gjeorgjievski M, Amin MB, Cappell MS. Characteristic clinical features of Aspergillus appendicitis: Case report and literature review. World J Gastroenterol 2015; 21(44): 12713-12721
URL http://www.wjgnet.com/1007-9327/full/v21/i44/12713.htm
DOI http://dx.doi.org/10.3748/wjg.v21.i44.12713
Full Article (PDF) WJG-21-12713.pdf
Full Article (Word) WJG-21-12713.doc
Manuscript File 20319-Review.docx
Answering Reviewers 20319-Answering reviewers.pdf
Audio Core Tip 20319-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 20319-Conflict-of-interest statement.pdf
Copyright License Agreement 20319-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 20319-Institutional review board statement.pdf
Supplementary Material Supplementary_Material_20150601032603.docx
Peer-review Report 20319-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 20319-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 20319-Scientific misconduct check.pdf
Scientific Editor Work List 20319-Scientific editor work list.pdf