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Articles Published Processes
11/27/2015 2:08:00 PM | Browse: 1468 | Download: 2037
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Received |
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2015-06-02 10:01 |
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Peer-Review Started |
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2015-06-03 12:52 |
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To Make the First Decision |
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2015-07-10 14:36 |
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Return for Revision |
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2015-07-18 11:50 |
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Revised |
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2015-08-03 12:03 |
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Second Decision |
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2015-09-23 19:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-09-30 08:51 |
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Articles in Press |
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2015-09-30 08:52 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-11-09 14:59 |
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Publish the Manuscript Online |
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2015-11-27 14:01 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Evaluation of a multiplex PCR assay for detection of cytomegalovirus in stool samples from patients with ulcerative colitis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Saifun Nahar, Atsushi Iraha, Akira Hokama, Ayako Uehara, Gretchen Parrott, Tetsuya Ohira, Masatoshi Kaida, Tetsu Kinjo, Takeshi Kinjo, Tetsuo Hirata, Nagisa Kinjo and Jiro Fujita |
| Funding Agency and Grant Number |
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| Corresponding Author |
Akira Hokama, MD, PhD, Clinical Professor, Department of Endoscopy, University of the Ryukyus, 207 Uehara, Nishihara, Okinawa 903-0215,
Japan. hokama-a@med.u-ryukyu.ac.jp
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| Key Words |
Polymerase chain reaction; Ulcerative colitis; Cytomegalovirus; immunosuppressive drugs; Epstein-Barr virus |
| Core Tip |
Infection with cytomegalovirus (CMV) can cause exacerbation of ulcerative colitis (UC). Thus, early diagnosis of CMV infection is important. Although endoscopic biopsy is the best approach for the diagnosis of CMV infection, this procedure may be invasive for patients and damaging to the inflamed intestine. Our prospective study on the use of the qualitative multiplex PCR assay in stool samples revealed that CMV infection is significantly more prevalent in UC active patients with immunosuppressive drugs. The multiplex PCR assay for stool samples may prove useful, non-invasive method to exclude the presence of CMV infection in patients with active UC who are treated with immunosuppressive drugs.
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| Publish Date |
2015-11-27 14:01 |
| Citation |
Nahar S, Iraha A, Hokama A, Uehara A, Parrott G, Ohira T, Kaida M, Kinjo T, Kinjo T, Hirata T, Kinjo N, Fujita J. Evaluation of a multiplex PCR assay for detection of cytomegalovirus in stool samples from patients with ulcerative colitis. World J Gastroenterol 2015; 21(44): 12667-12675 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i44/12667.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i44.12667 |
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