Publication Name	World Journal of Cardiology
Manuscript ID	20360
Country	United States

Received	2015-06-02 10:03
Peer-Review Started	2015-06-04 15:17
To Make the First Decision	2015-07-28 10:43
Return for Revision	2015-08-08 14:22
Revised	2015-08-22 06:44
Second Decision	2015-09-29 17:20
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-27 18:31
Articles in Press	2015-10-27 18:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-10 10:33
Publish the Manuscript Online	2015-12-24 17:39

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Mechanical valve obstruction: Review of diagnostic and treatment strategies
Manuscript Source	Invited Manuscript
All Author List	Jason Salamon, Jerson Munoz-Mendoza, Jared J Liebelt and Cynthia C Taub
Funding Agency and Grant Number
Corresponding Author	Jason Salamon, MD, Department of Cardiology, Montefiore Medical Center, 211 E 210th Street, Bronx, NY 10467, United States. jason.salamon@med.einstein.yu.edu
Key Words	Prosthetic valve thrombosis; Pannus overgrowth; Thrombolysis; Prosthetic valve obstruction; Echocardiography
Core Tip	Prosthetic valve obstruction (PVO), while rare, is a dreaded complication of mechanical valve replacement. Careful clinical and multiple non-invasive imaging modalities are necessary to assess suspected PVO and evaluate for pannus overgrowth or valve thrombosis. Unlike pannus overgrowth, prosthetic valve thrombosis is more common, occurs earlier in the post-op period, is frequently related to inadequate anti-coagulation, and can often be treated through non-invasive thrombolysis. While the current understanding of pannus overgrowth remains elusive, future clarification of its pathophysiology may allow for the development of non-invasive therapeutic options.
Publish Date	2015-12-24 17:39
Citation	Salamon J, Munoz-Mendoza J, Liebelt JJ, Taub CC. Mechanical valve obstruction: Review of diagnostic and treatment strategies. World J Cardiol 2015; 7(12): 875-881
URL	http://www.wjgnet.com/1949-8462/full/v7/i12/875.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i12.875

Full Article (PDF)	WJC-7-875.pdf
Full Article (Word)	WJC-7-875.doc
Manuscript File	20360-Review.docx
Answering Reviewers	20360-Answering reviewers.pdf
Audio Core Tip	20360-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20360-Conflict-of-interest statement.pdf
Copyright License Agreement	20360-Copyright assignment.pdf
Peer-review Report	20360-Peer-review(s).pdf
Scientific Misconduct Check	20360-Scientific misconduct check.pdf
Scientific Editor Work List	20360-Scientific editor work list.pdf