Publication Name	World Journal of Gastroenterology
Manuscript ID	2041
Country	China

Received	2013-01-23 08:35
Peer-Review Started	2013-01-24 11:33
To Make the First Decision	2013-03-04 11:55
Return for Revision	2013-03-08 09:27
Revised	2013-03-28 20:49
Second Decision	2013-07-18 14:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-07-19 01:00
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-08-01 10:31
Publish the Manuscript Online	2013-08-19 18:22

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Autobiography
Article Title	HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection
Manuscript Source	Invited Manuscript
All Author List	Chun-Qing Deng, Guo-Hong Deng and Yu-Ming Wang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 30972598 State Key Project Specialized for Infectious Diseases 2012ZX10002-004 TMMU Key Project for Clinical Study 2012XLC-005
Corresponding Author	Yu-Ming Wang, Professor, Institute of Infectious Diseases, Southwest Hospital, Third Military Medical University, No. 35 Gaotanyanzheng Street, Shapingba District, Chongqing 400038, China. wym417@163.com
Key Words	High mobility group box chromosomal protein 1; Hepatitis B virus; Polymorphism; Intron
Core Tip	We analyzed the relationship between the high mobility group box chromosomal protein 1 (HMGB1) 1176 G/C polymorphism and the susceptibility and outcome to hepatitis B virus (HBV) infection in a large hospital-based case-control study. Our results indicated that patients with 1176G/G genotype of HMGB1 gene are more likely to have a progressive status in HBV infection. Our study emphasizes the importance of HMGB1 in the pathophysiology of HBV-related diseases on the population level and will provide researchers new clue for the further basic research in pathogenesis of chronic HBV infection.
Publish Date	2013-08-19 18:22
Citation	Deng CQ, Deng GH, Wang YM. HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection. World J Gastroenterol 2013; 19(31): 5144-5149
URL	http://www.wjgnet.com/1007-9327/full/v19/i31/5144.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i31.5144

Full Article (PDF)	WJG-19-5144.pdf
Manuscript File	2041-Review.doc
Answering Reviewers	2041-Answering reviewers.pdf
Copyright License Agreement	2041-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	2041-Language certificate.doc
Peer-review Report	2041-Peer review.pdf
Scientific Editor Work List	2041-Scientific editor work list.doc