Publication Name	World Journal of Gastroenterology
Manuscript ID	20434
Country	China

Received	2015-06-04 09:40
Peer-Review Started	2015-06-06 15:02
To Make the First Decision	2015-07-10 14:36
Return for Revision	2015-07-13 19:44
Revised	2015-07-20 09:58
Second Decision	2015-09-13 22:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-15 14:01
Articles in Press	2015-09-15 14:01
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-09-21 07:19
Typeset the Manuscript	2015-11-16 16:38
Publish the Manuscript Online	2015-12-06 13:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Critical Care Medicine
Manuscript Type	Basic Study
Article Title	Biliary tract external drainage protects against intestinal barrier injury in hemorrhagic shock rats
Manuscript Source	Unsolicited Manuscript
All Author List	Lu Wang, Bing Zhao, Ying Chen, Li Ma, Er-Zhen Chen and En-Qiang Mao
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81171789
Corresponding Author	En-Qiang Mao, MD, PhD, Professor of Medicine, Department of Emergency Intensive Care Unit, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Road Number Two, Shanghai 200025, China. maoeq@yeah.net
Key Words	Hemorrhagic shock; Biliary tract external drainage; Occludin; Claudin-1; D-lactate
Core Tip	Our previous studies demonstrated that biliary tract external drainage decreased proinflammatory cytokine production and relieved tissue damage in rat models of hemorrhagic shock. In this research, we found that biliary tract external drainage increased the expression levels of occludin and claudin-1 and decreased plasma D-lactate and lipopolysaccharide levels under hemorrhagic shock conditions. These results demonstrate that biliary tract external drainage protects against intestinal barrier injury in hemorrhagic shock rats.
Publish Date	2015-12-06 13:18
Citation	Wang L, Zhao B, Chen Y, Ma L, Chen EZ, Mao EQ. Biliary tract external drainage protects against intestinal barrier injury in hemorrhagic shock rats. World J Gastroenterol 2015; 21(45): 12800-12813
URL	http://www.wjgnet.com/1007-9327/full/v21/i45/12800.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i45.12800

Full Article (PDF)	WJG-21-12800.pdf
Full Article (Word)	WJG-21-12800.doc
Manuscript File	20434-Review.docx
Answering Reviewers	20434-Answering reviewers.pdf
Audio Core Tip	20434-Audio core tip.mp3
Biostatistics Review Certificate	20434-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	20434-Conflict-of-interest statement.pdf
Copyright License Agreement	20434-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	20434-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	20434-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	20434-Language certificate.pdf
Peer-review Report	20434-Peer-review(s).pdf
Scientific Misconduct Check	20434-Scientific misconduct check.pdf
Scientific Editor Work List	20434-Scientific editor work list.pdf