Publication Name	World Journal of Gastroenterology
Manuscript ID	20484
Country	United States

Received	2015-06-07 14:56
Peer-Review Started	2015-06-08 17:37
To Make the First Decision	2015-07-13 15:23
Return for Revision	2015-07-17 16:56
Revised	2015-07-26 05:02
Second Decision	2015-09-12 22:04
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-14 11:36
Articles in Press	2015-09-14 11:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-10 12:25
Publish the Manuscript Online	2015-10-23 15:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Disease monitoring in inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Shannon Chang, Lisa Malter and David Hudesman
Funding Agency and Grant Number
Corresponding Author	Dr. David Hudesman, Director of the Inflammatory Bowel Disease Program, Division of Gastroenterology, NYU Langone Medical Center, 240 East 38th Street, Floor 23, New York University, New York City, Ny 10016, United States. david.hudesman@nyumc.org
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Fecal calprotectin; C-reactive protein; Fecal immunochemical test; Biomarkers; Remission; Postoperative recurrence
Core Tip	C-reactive protein (CRP) is not specific for intestinal inflammation but does have modest correlation with clinical and endoscopic findings in inflammatory bowel disease patients. CRP can be falsely low despite active mucosal inflammation and is more reliable in cases of transmural inflammation. Fecal calprotectin (FC) is more specific than CRP for intestinal inflammation, except in isolated ileal disease. FC better correlates with endoscopic findings than CRP and is useful in monitoring Crohn’s patients for postoperative recurrence. Optimal FC cutoffs are still being determined.
Publish Date	2015-10-23 15:45
Citation	Chang S, Malter L, Hudesman D. Disease monitoring in inflammatory bowel disease. World J Gastroenterol 2015; 21(40): 11246-11259
URL	http://www.wjgnet.com/1007-9327/full/v21/i40/11246.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i40.11246

Full Article (PDF)	WJG-21-11246.pdf
Full Article (Word)	WJG-21-11246.doc
Manuscript File	20484-Review.docx
Answering Reviewers	20484-Answering reviewers.pdf
Audio Core Tip	20484-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20484-Conflict-of-interest statement.pdf
Copyright License Agreement	20484-Copyright assignment.pdf
Peer-review Report	20484-Peer-review(s).pdf
Scientific Misconduct Check	20484-Scientific misconduct check.pdf
Scientific Editor Work List	20484-Scientific editor work list.pdf