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Articles Published Processes
12/15/2015 12:22:00 PM | Browse: 916 | Download: 1356
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Received |
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2015-06-08 15:57 |
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Peer-Review Started |
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2015-06-11 09:11 |
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To Make the First Decision |
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2015-07-10 15:15 |
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Return for Revision |
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2015-07-14 18:28 |
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Revised |
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2015-07-17 09:03 |
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Second Decision |
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2015-09-28 16:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-09-30 10:35 |
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Articles in Press |
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2015-09-30 10:36 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2015-11-23 10:12 |
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Publish the Manuscript Online |
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2015-12-15 12:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Observational Study |
| Article Title |
Development of Fok-I based nested polymerase chain reaction-restriction fragment length polymorphism analysis for detection of hepatitis B virus X region V5M mutation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong Kim, Seok-Hyun Hong, Seoung-Ae Lee, Jeong-Ryeol Gong and Bum-Joon Kim |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Research Foundation of Korea |
2013-005810 |
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| Corresponding Author |
Bum-Joon Kim, Professor, Department of Biomedical Sciences, Microbiology and Immunology, and Liver Research Institute, Seoul National University College of Medicine, Seoul 110-799, South Korea. kbumjoon@snu.ac.kr |
| Key Words |
Hepatitis B virus; X antigen; Polymerase chain reaction-restriction fragment length polymorphism analysis; V5M mutation; Hepatocellur carcinoma |
| Core Tip |
In the present study, we developed a reliable and cost-effective Fok-I nested polymerase chain reaction-restriction fragment length polymorphism analysis (PRA) method for the detection of V5M from chronic patients with genotype C2 infection. In addition, our epidemiological data based on the Fok-I nested PRA method strongly support the previous reports that V5M may play a very pivotal role in hepato-carcinogenesis, at least in chronic patients infected with genotype C2. |
| Publish Date |
2015-12-15 12:22 |
| Citation |
Kim H, Hong SH, Lee SA, Gong JR, Kim BJ. Development of Fok-I based nested polymerase chain reaction-restriction fragment length polymorphism analysis for detection of hepatitis B virus X region V5M mutation. World J Gastroenterol 2015; 21(47): 13360-13367 |
| URL |
http://www.wjgnet.com/1007-9327/full/v21/i47/13360.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v21.i47.13360 |
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