Publication Name	World Journal of Gastroenterology
Manuscript ID	20517
Country	China

Received	2015-06-09 09:35
Peer-Review Started	2015-06-11 10:24
To Make the First Decision	2015-07-10 15:15
Return for Revision	2015-07-14 18:40
Revised	2015-08-06 14:07
Second Decision	2015-10-10 18:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-16 09:09
Articles in Press	2015-10-16 09:09
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-05 08:35
Typeset the Manuscript	2015-12-10 13:35
Publish the Manuscript Online	2015-12-24 11:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Basic Study
Article Title	Neural mechanism of gastric motility regulation by electroacupuncture at RN12 and BL21: A paraventricular hypothalamic nucleus-dorsal vagal complex-vagus nerve-gastric channel pathway
Manuscript Source	Unsolicited Manuscript
All Author List	Hao Wang, Wen-Jian Liu, Guo-Ming Shen, Meng-Ting Zhang, Shun Huang and Ying He
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 81473784 Natural Science Foundation of Anhui Province 1408085MH166 Natural Science Foundation of Anhui University of Traditional Chinese Medicine 2013qn002
Corresponding Author	Guo-Ming Shen, Professor, Institute of Integrated Chinese and Western Medicine, Anhui University of Traditional Chinese Medicine, No. 70, Meishan Road, Hefei 230038, Anhui Province, China. shengm_66@163.com
Key Words	Dorsal vagal complex; Gastrin receptor; Motilin receptor; Neuronal firing activity; Paraventricular hypothalamic nucleus; RN12; BL21
Core Tip	This study supports the “targeted convergence” hypothesis: Shu-acu point and Mu-acu point signals gather not only in spinal cord but also evince a ‘targeted convergence’ in brain stem and hypothalamus. We determined that the signals induced by electro-acupuncture (EA) stimulation of gastric Shu and Mu points gather in the dorsal vagal complex (DVC) and paraventricular hypothalamic nucleus (PVN), increasing levels of gastrointestinal hormones and their receptors in the PVN and gastric antrum to regulate gastric motility. We hypothesize that EA at gastric Shu and Mu points regulates gastric motility, which may be achieved through the PVN-DVC-vagus-gastric pathway.
Publish Date	2015-12-24 11:11
Citation	Wang H, Liu WJ, Shen GM, Zhang MT, Huang S, He Y. Neural mechanism of gastric motility regulation by electroacupuncture at RN12 and BL21: A paraventricular hypothalamic nucleus-dorsal vagal complex-vagus nerve-gastric channel pathway. World J Gastroenterol 2015; 21(48): 13480-13489
URL	http://www.wjgnet.com/1007-9327/full/v21/i48/13480.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i48.13480

Full Article (PDF)	WJG-21-13480.pdf
Full Article (Word)	WJG-21-13480.doc
Manuscript File	20517-Review.doc
Answering Reviewers	20517-Answering reviewers.pdf
Audio Core Tip	20517-Audio core tip.mp3
Biostatistics Review Certificate	20517-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	20517-Conflict-of-interest statement.pdf
Copyright License Agreement	20517-Copyright assignment.pdf
Institutional Animal Care and Use Committee Approval Form or Document	20517-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document	20517-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	20517-Language certificate.pdf
Peer-review Report	20517-Peer-review(s).pdf
Scientific Misconduct Check	20517-Scientific misconduct check.pdf
Scientific Editor Work List	20517-Scientific editor work list.pdf