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Articles Published Processes
3/4/2016 7:53:00 PM | Browse: 1309 | Download: 3065
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Received |
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2015-06-10 08:49 |
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Peer-Review Started |
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2015-06-12 10:15 |
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To Make the First Decision |
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2015-11-05 10:47 |
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Return for Revision |
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2015-11-06 09:24 |
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Revised |
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2015-12-04 03:24 |
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Second Decision |
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2015-12-31 07:56 |
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Accepted by Journal Editor-in-Chief |
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2016-01-01 20:30 |
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Accepted by Executive Editor-in-Chief |
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2016-01-11 13:05 |
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Articles in Press |
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2016-01-11 13:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-02-26 09:29 |
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Publish the Manuscript Online |
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2016-03-04 19:53 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Basic Study |
| Article Title |
Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Enas A Abd El-Haleim, Ashraf K Bahgat and Samira Saleh |
| Funding Agency and Grant Number |
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| Corresponding Author |
Enas A Abd El-Haleim, MSc, Assistant Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo University Rd, Cairo 11562, Egypt. enaselshemy@hotmail.com |
| Key Words |
Fructose; Nonalcoholic steatohepatitis; Suppressor of cytokine signaling-3; Sterol regulatory element binding protein-1c; Fatty acid synthase; Malonyl CoA decarboxylase; Leptin; Adiponectin; Transforming growth factor-β; Tumor necrosis factor-α |
| Core Tip |
The current work may justify the use of lower doses of fenofibrate in combination with resveratrol to protect the liver from fructose induced hepatic steatosis and damage. The synergistic effect may be due to antioxidant, anti-inflammatory and anti-hyperlipidemic effect of resveratrol. As an add-on therapy, resveratrol can augment the beneficial outcome of a lower dose of fenofibrate and reduces its toxic or side effects. |
| Publish Date |
2016-03-04 19:53 |
| Citation |
Abd El-Haleim EA, Bahgat AK, Saleh S. Resveratrol and fenofibrate ameliorate fructose-induced nonalcoholic steatohepatitis by modulation of genes expression. World J Gastroenterol 2016; 22(10): 2931-2948 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i10/2931.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i10.2931 |
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