Publication Name	World Journal of Gastroenterology
Manuscript ID	20551
Country	United States

Received	2015-06-10 08:43
Peer-Review Started	2015-06-12 11:53
To Make the First Decision	2015-10-14 17:02
Return for Revision	2015-10-15 14:05
Revised	2015-11-05 08:44
Second Decision	2015-11-26 16:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-08 16:33
Articles in Press	2015-12-08 16:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-31 14:18
Publish the Manuscript Online	2016-01-15 14:54

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Frontier
Article Title	Bisphosphonates as potential adjuvants for patients with cancers of the digestive system
Manuscript Source	Invited Manuscript
All Author List	Celina Ang, Erin Doyle and Andrea Branch
Funding Agency and Grant Number
Corresponding Author	Celina Ang, MD, Associate Professor, Department of Medicine, Division of Hematology/Oncology, Icahn School of Medicine at Mount Sinai, Box 1079, New York, NY 10029, United States. andrea.branch@mssm.edu
Key Words	Bisphosphonates; Cancer; Gastrointestinal; Hepatobiliary; Human epidermal growth factor
Core Tip	Bisphosphonates demonstrate antineoplastic activity in various malignancies but have received little attention in cancers of the digestive tract. We review the preclinical and clinical experience with bisphosphonates in digestive cancers and discuss their potential therapeutic application in this disease group, particularly in the context of recent data on bisphosphonate-induced inhibition of human epidermal growth factor receptor signaling.
Publish Date	2016-01-15 14:54
Citation	Ang C, Doyle E, Branch A. Bisphosphonates as potential adjuvants for patients with cancers of the digestive system. World J Gastroenterol 2016; 22(3): 906-916
URL	http://www.wjgnet.com/1007-9327/full/v22/i3/906.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i3.906

Full Article (PDF)	WJG-22-906.pdf
Full Article (Word)	WJG-22-906.doc
Manuscript File	20551-Review.doc
Answering Reviewers	20551-Answering reviewers.pdf
Audio Core Tip	20551-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20551-Conflict-of-interest statement.pdf
Copyright License Agreement	20551-Copyright assignment.pdf
Peer-review Report	20551-Peer-review(s).pdf
Scientific Misconduct Check	20551-Scientific misconduct check.pdf
Scientific Editor Work List	20551-Scientific editor work list.pdf