Publication Name	World Journal of Translational Medicine
Manuscript ID	206
Country	United States

Received	2012-08-14 08:16
Peer-Review Started	2012-08-27 12:02
To Make the First Decision
Return for Revision
Revised
Second Decision	2013-04-27 10:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-27 23:58
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-06-04 17:15
Publish the Manuscript Online	2013-07-15 16:32

ISSN	2220-6132 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Research & Experimental Medicine
Manuscript Type	Autobiography
Article Title	High-potency sucralfate prevents and rapidly reverses chemo-radiation mucositis in a patient with stage 4b head and neck cancer
Manuscript Source	Invited Manuscript
All Author List	Ricky W McCullough
Funding Agency and Grant Number	Funding Agency Grant Number Translation Medicine Research Compassionate Use Program of MMI 2006-001
Corresponding Author	Ricky W McCullough, MD, MSc, Center for Translational Medicine Research, Mueller Medical International LLC, 830 Chaulkstone Avenue, Box 169, Foster, RI 02825, United States. glencopelph@aol.com
Key Words	Sucralfate; Mucositis; Chemoradiation; Immuno-modulation; Cytokines; Intra-epithelial lymphocytes; Growth factors
Core Tip	Mucositis is a debilitating and costly consequence of chemo-radiation. Most mucositis treatments are palliative. Conversely, high-potency sucralfate (HPS) may be definitive. Patients with stage 4b head neck cancer, at high risk for developing mucositis, require gastrostomy tubes as an alternative to oral feeding. The use of HPS in this cancer patient prevented mucositis, allowing continuance of standard oral diet. Midway through chemo-radiation, though noncompliant discontinuation of HPS, by patient led to the emergence oral and alimentary mucositis, 2 d following resumption of HPS, mucositis disappeared, a normal oral diet was maintained and no analgesia was required.
Publish Date	2013-07-15 16:32
Citation	McCullough RW. High-potency sucralfate prevents and rapidly reverses chemo-radiation mucositis in a patient with stage 4b head and neck cancer. World J Transl Med 2013; 2(2): 13-21
URL	http://www.wjgnet.com/2220-6132/full/v2/i2/13.htm
DOI	http://dx.doi.org/10.5528/wjtm.v2.i2.13

Full Article (PDF)	WJTM-2-13.pdf
Manuscript File	206-Review.doc
Answering Reviewers	206-Answering reviewers.pdf
Copyright License Agreement	206-Copyright assignment.pdf
Peer-review Report	206-Peer review(s).pdf
Scientific Editor Work List	206-Scientific editor work list.doc