Publication Name	World Journal of Cardiology
Manuscript ID	20650
Country	Italy

Received	2015-06-15 08:29
Peer-Review Started	2015-06-17 08:14
To Make the First Decision	2015-07-27 15:52
Return for Revision	2015-08-04 14:29
Revised	2015-09-04 06:46
Second Decision	2015-10-08 12:23
Accepted by Journal Editor-in-Chief	2015-10-09 15:30
Accepted by Executive Editor-in-Chief	2015-10-19 15:31
Articles in Press	2015-10-19 15:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-17 09:18
Publish the Manuscript Online	2015-12-24 17:39

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Myocardial perfusion echocardiography and coronary microvascular dysfunction
Manuscript Source	Invited Manuscript
All Author List	Giuseppe Barletta and Maria Riccarda Del Bene
Funding Agency and Grant Number
Corresponding Author	Giuseppe Barletta, MD, FESC, Cardio-Thoracic and Vascular Department, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla, 50134 Florence, Italy. barlettagius@tiscali.it
Key Words	Contrast echocardiography; Myocardial perfusion; Myocardial ischemia; Microvascular angina; Coronary flow
Core Tip	Diagnostic work-up of coronary heart disease is evolving to include evaluations of the coronary microcirculation in addition to the imaging of obstructive atherosclerosis of coronary arteries and its eventual effects. Functional assessments of coronary microvasculature have become the challenge. Myocardial contrast echocardiography (MCE) emerged as a promising tool several years ago to detect myocardial perfusion abnormalities and quantify coronary blood flow. MCE compared favorably with other expensive techniques, and it accurately evaluated coronary microvascular reserve and dysfunction in research studies. However, its daily use in clinical practice is not established. Therefore, the future of this technique is questionable.
Publish Date	2015-12-24 17:39
Citation	Barletta G, Del Bene MR. Myocardial perfusion echocardiography and coronary microvascular dysfunction. World J Cardiol 2015; 7(12): 861-874
URL	http://www.wjgnet.com/1949-8462/full/v7/i12/861.htm
DOI	http://dx.doi.org/10.4330/wjc.v7.i12.861

Full Article (PDF)	WJC-7-861.pdf
Full Article (Word)	WJC-7-861.doc
Manuscript File	20650-Review.docx
Answering Reviewers	20650-Answering reviewers.pdf
Audio Core Tip	20650-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20650-Conflict-of-interest statement.pdf
Copyright License Agreement	20650-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20650-Language certificate.pdf
Peer-review Report	20650-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20650-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20650-Scientific misconduct check.pdf
Scientific Editor Work List	20650-Scientific editor work list.pdf