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12/14/2015 9:02:00 PM | Browse: 1066 | Download: 973
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 20671
Country/Territory India
Received
2015-06-16 09:42
Peer-Review Started
2015-06-17 14:08
To Make the First Decision
2015-07-27 18:36
Return for Revision
2015-07-31 18:43
Revised
2015-08-07 15:07
Second Decision
2015-10-13 09:01
Accepted by Journal Editor-in-Chief
2015-10-14 02:41
Accepted by Company Editor-in-Chief
2015-10-27 18:01
Articles in Press
2015-10-27 18:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-12-03 19:27
Publish the Manuscript Online
2015-12-14 21:02
ISSN 1948-5204 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Targeting cancer testis antigens for biomarkers and immunotherapy in colorectal cancer: Current status and challenges
Manuscript Source Invited Manuscript
All Author List Anil Suri, Nirmala Jagadish, Shikha Saini and Namita Gupta
Funding Agency and Grant Number
Funding Agency Grant Number
Indo-UK Cancer Research Program BT/IN/UK/NII/2006
Centre for Molecular Medicine BT/PR/14549/MED/14/1291
NII-core funding, Department of Biotechnology, Government of India
Corresponding Author Dr. Anil Suri, FNASc, FAMS, Cancer Microarray, Genes and Proteins Laboratory, National Institute of Immunology, Aruna Asaf Ali Marg, New Delhi 110067, India. anil@nii.res.in
Key Words Cancer testis antigens; Colorectal cancer; Testis specific genes; Biomarkers; Immunotherapy
Core Tip Despite of the availability of enormous tumor antigens, there is a dearth of targets for biomarkers and immunotherapy for clinical cancer management. Cost-effectiveness and invasiveness associated with colonoscopy hinders its implications in less developed and developing countries. Colorectal cancer treatment including surgery and radiation has significant side effects on normal tissues. Recently a new category of antigens has been discovered which are expressed in tumor cells but not in normal tissues except the immuno-privileged testis. Targeting such antigens would be specific to the cancer cells with no deleterious effects on normal cells. Scope of these magic bullets in colorectal cancer is discussed in this review.
Publish Date 2015-12-14 21:02
Citation Suri A, Jagadish N, Saini S, Gupta N. Targeting cancer testis antigens for biomarkers and immunotherapy in colorectal cancer: Current status and challenges. World J Gastrointest Oncol 2015; 7(12): 492-502
URL http://www.wjgnet.com/1948-5204/full/v7/i12/492.htm
DOI http://dx.doi.org/10.4251/wjgo.v7.i12.492
Full Article (PDF) WJGO-7-492.pdf
Full Article (Word) WJGO-7-492.doc
Manuscript File 20671-Review.docx
Answering Reviewers 20671-Answering reviewers.pdf
Audio Core Tip 20671-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 20671-Conflict-of-interest statement.pdf
Copyright License Agreement 20671-Copyright assignment.pdf
Peer-review Report 20671-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 20671-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 20671-Scientific misconduct check.pdf
Scientific Editor Work List 20671-Scientific editor work list.pdf