Publication Name	World Journal of Experimental Medicine
Manuscript ID	20697
Country	Italy

Received	2015-06-16 16:09
Peer-Review Started	2015-06-20 14:59
To Make the First Decision	2015-07-27 18:35
Return for Revision	2015-07-31 17:43
Revised	2015-08-07 17:21
Second Decision	2015-10-21 17:35
Accepted by Journal Editor-in-Chief	2015-10-21 18:21
Accepted by Executive Editor-in-Chief	2015-11-04 17:38
Articles in Press	2015-11-04 17:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-11-13 18:35
Publish the Manuscript Online	2015-11-23 08:36

ISSN	2220-315x (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Enzymatic antioxidant system in vascular inflammation and coronary artery disease
Manuscript Source	Invited Manuscript
All Author List	Valter Lubrano and Silvana Balzan
Funding Agency and Grant Number
Corresponding Author	Valter Lubrano, PhD, Department of Laboratory Medicine, Fondazione G. Monasterio CNR-Regione Toscana, Via Moruzzi n° 1, 56124 Pisa, Italy. walterl@ftgm.it
Key Words	Superoxide dismutase; Catalase; Glutathione peroxidase; Antioxidant enzyme; Coronary artery disease; Reactive oxygen species; Vascular inflammation
Core Tip	This review shows that antioxidant enzymes are very important factors for the prevention and treatment of atherosclerotic disease, but more studies are required to understand whether they can be used as markers for diagnosis of coronary artery disease. The presence of polymorphic genes that increases the activity and expression of these enzymes can be considered important for the development of new therapeutic strategies. In our opinion further efforts should be directed especially on this last point, in order to find new therapies to increase the function of antioxidant enzymes in metabolic disease or other risk factors.
Publish Date	2015-11-23 08:36
Citation	Lubrano V, Balzan S. Enzymatic antioxidant system in vascular inflammation and coronary artery disease. World J Exp Med 2015; 5(4): 218-224
URL	http://www.wjgnet.com/2220-315X/full/v5/i4/218.htm
DOI	http://dx.doi.org/10.5493/wjem.v5.i4.218

Full Article (PDF)	WJEM-5-218.pdf
Full Article (Word)	WJEM-5-218.doc
Manuscript File	20697-Review.doc
Answering Reviewers	20697-Answering reviewers.pdf
Audio Core Tip	20697-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20697-Conflict-of-interest statement.pdf
Copyright License Agreement	20697-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20697-Language certificate.pdf
Peer-review Report	20697-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20697-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20697-Scientific misconduct check.pdf
Scientific Editor Work List	20697-Scientific editor work list.pdf