Publication Name	World Journal of Methodology
Manuscript ID	20708
Country	India

Received	2015-06-17 08:30
Peer-Review Started	2015-06-18 08:24
To Make the First Decision	2015-09-23 17:25
Return for Revision	2015-10-08 15:39
Revised	2015-11-24 19:15
Second Decision	2016-03-16 19:06
Accepted by Journal Editor-in-Chief	2016-03-16 20:43
Accepted by Company Editor-in-Chief	2016-03-23 16:32
Articles in Press	2016-03-23 16:32
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-05-17 15:17
Publish the Manuscript Online	2016-06-23 18:00

ISSN	2222-0682 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Reproductive Biology
Manuscript Type	Case Control Study
Article Title	Mild oxidative stress is beneficial for sperm telomere length maintenance
Manuscript Source	Invited Manuscript
All Author List	Swetasmita Mishra, Rajeev Kumar, Neena Malhotra, Neeta Singh and Rima Dada
Funding Agency and Grant Number	Funding Agency Grant Number Department of Biotechnology (DBT), Government of India 1369
Corresponding Author	Rima Dada, MD, PhD, Professor, Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, New Delhi 110029, India. rima_dada@rediffmail.com
Key Words	Telomere; Oxidative stress; Reactive oxygen species; Infertility; 8-Isoprostane
Core Tip	In the present study we found that infertile men experienced oxidative stress evident from increased seminal reactive oxygen species and 8-Isoprostane levels. Infertile men also had shorter telomeres as compared to the controls. Severe oxidative stress negatively affected sperm telomere length but surprisingly mild oxidative stress resulted in lengthening of telomere and thus may aid in maintaining genomic integrity. To the best of our knowledge we are the first to report positive effect of mild oxidative stress on sperm telomere length.
Publish Date	2016-06-23 18:00
Citation	Mishra S, Kumar R, Malhotra N, Singh N, Dada R. Mild oxidative stress is beneficial for sperm telomere length maintenance. World J Methodol 2016; 6(2): 163-170
URL	http://www.wjgnet.com/2222-0682/full/v6/i2/163.htm
DOI	http://dx.doi.org/10.5662/wjm.v6.i2.163

Full Article (PDF)	WJM-6-163.pdf
Full Article (Word)	WJM-6-163.doc
Manuscript File	20708-Review.doc
Answering Reviewers	20708-Answering reviewers.pdf
Audio Core Tip	20708-Audio core tip.mp3
Biostatistics Review Certificate	20708-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	20708-Conflict-of-interest statement.pdf
Copyright License Agreement	20708-Copyright assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	20708-Grant application form(s).pdf
Institutional Review Board Approval Form or Document	20708-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	20708-Language certificate.pdf
Peer-review Report	20708-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20708-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20708-Scientific misconduct check.pdf
Scientific Editor Work List	20708-Scientific editor work list.pdf