Publication Name	World Journal of Clinical Cases
Manuscript ID	20710
Country	Spain

Received	2015-06-17 08:26
Peer-Review Started	2015-06-17 19:53
To Make the First Decision	2015-09-28 12:20
Return for Revision	2015-09-29 09:11
Revised	2015-10-09 19:59
Second Decision	2015-11-30 09:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-11 16:17
Articles in Press	2015-12-11 16:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-23 10:50
Publish the Manuscript Online	2016-01-26 15:14

ISSN	2307-8960 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Neurosciences
Manuscript Type	Editorial
Article Title	Stroke and sleep-disordered breathing: A relationship under construction
Manuscript Source	Invited Manuscript
All Author List	Olga Parra and Adrià Arboix
Funding Agency and Grant Number
Corresponding Author	Adrià Arboix, MD, PhD, Cerebrovascular Division, Service of Neurology, University of Barcelona, Hospital del Sagrat Cor, C/ Viladomat 288, E-08029 Barcelona, Spain. aarboix@hscor.com
Key Words	Apnea-hypopnea index; Cardiovascular risk factors; Continuous positive airway pressure; Ischemic stroke; Lacunar infarction; Sleep disordered
Core Tip	Sleep disorders including obstructive sleep apnea are associated with an increased risk for a number of cardiovascular diseases, notably acute cere-brovascular events. A number of studies have shown a high prevalence of sleep-related breathing disorders in patients with stroke. A decrease in cerebral perfusion and increased coagulability related to metabolic, hematological and hemodynamic changes occuring in the presence of sleep-related breathing disorders are proposed as potential mechanisms in the pathogenesis of stroke. Early diagnosis and prompt therapeutic mea-sures, including continuous positive airway pressure are necessary to reduce the stroke risk associated with sleep disorders. Sleep-related breating disorders should be considered modifiable risk factors for stroke, although they are frequenty underdiagnosed. The relationship between sleep breathing disorders and stroke should be further investigated for improving primary and secondary stroke prevention strategies and to contribute to reduce the global burden of stroke.
Publish Date	2016-01-26 15:14
Citation	Parra O, Arboix A. Stroke and sleep-disordered breathing: A relationship under construction. World J Clin Cases 2016; 4(2): 33-37
URL	http://www.wjgnet.com/2307-8960/full/v4/i2/33.htm
DOI	http://dx.doi.org/10.12998/wjcc.v4.i2.33

Full Article (PDF)	WJCC-4-33.pdf
Full Article (Word)	WJCC-4-33.doc
Manuscript File	20710-Review.doc
Answering Reviewers	20710-Answering reviewers.pdf
Audio Core Tip	20710-Audio core tip.MP3
Conflict-of-Interest Disclosure Form	20710-Conflict-of-interest statement.pdf
Copyright License Agreement	20710-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20710-Language certificate.pdf
Peer-review Report	20710-Peer-review(s).pdf
Scientific Misconduct Check	20710-Scientific misconduct check.pdf
Scientific Editor Work List	20710-Scientific editor work list.pdf