Publication Name	World Journal of Clinical Oncology
Manuscript ID	20744
Country	France

Received	2015-06-22 16:07
Peer-Review Started	2015-06-27 18:34
To Make the First Decision	2015-07-26 17:45
Return for Revision	2015-07-31 16:01
Revised	2015-08-14 20:42
Second Decision	2016-02-29 09:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2016-03-14 11:52
Articles in Press	2016-03-14 11:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-23 17:30
Publish the Manuscript Online	2016-04-07 11:01

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Minireviews
Article Title	Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy
Manuscript Source	Invited Manuscript
All Author List	Agnès Tallet, Eric Lambaudie, Monique Cohen, Mathieu Minsat, Marie Bannier, Michel Resbeut and Gilles Houvenaeghel
Funding Agency and Grant Number
Corresponding Author	Gilles Houvenaeghel, MD, Departement of Surgery, Institut Paoli Calmettes and CRCM, 232 Bd de Sainte Marguerite, 13009 Marseille, France. houvenaeghelg@ipc.unicancer.fr
Key Words	Breast cancer; Micrometastases; Axillary lymph node dissection; Radiotherapy; Isolated tumor cells
Core Tip	Sentinel lymph-node biopsy has led to a shift in lymph-node staging, due to the emergence of new entities namely micro-metastases and isolated tumor cells. The prognostic significance of this low positivity in axillary lymph nodes is currently debated, as is, therefore its management. This review provides updates evidence-based medicine data to take into account for treatment decision-making in this setting, discussing several loco-regional therapeutic strategies based on recent clinical trials results, particularly completion axillary dissection, axillary irradiation, regional nodes irradiation, with according to systemic treatment, with the goal to help physicians in daily practice.
Publish Date	2016-04-07 11:01
Citation	Tallet A, Lambaudie E, Cohen M, Minsat M, Bannier M, Resbeut M, Houvenaeghel G. Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy. World J Clin Oncol 2016; 7(2): 243-252
URL	http://www.wjgnet.com/2218-4333/full/v7/i2/243.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i2.243

Full Article (PDF)	WJCO-7-243.pdf
Full Article (Word)	WJCO-7-243.doc
Manuscript File	20744-Review.docx
Answering Reviewers	20744-Answering reviewers.pdf
Audio Core Tip	20744-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	20744-Conflict-of-interest statement.pdf
Copyright License Agreement	20744-Copyright assignement.pdf
Peer-review Report	20744-Peer-review(s).pdf
Scientific Misconduct Check	20744-Scientific misconduct check.pdf
Scientific Editor Work List	20744-Scientific editor work list.pdf