Publication Name	World Journal of Gastroenterology
Manuscript ID	20805
Country	Italy

Received	2015-06-23 08:57
Peer-Review Started	2015-06-26 08:25
To Make the First Decision	2015-09-11 09:22
Return for Revision	2015-09-15 10:35
Revised	2015-10-13 18:48
Second Decision	2015-10-23 16:45
Accepted by Journal Editor-in-Chief	2015-10-24 04:10
Accepted by Executive Editor-in-Chief	2015-11-09 17:04
Articles in Press	2015-11-09 17:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-16 18:26
Publish the Manuscript Online	2016-01-06 16:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Topic Highlights
Article Title	Integration of genome scale data for identifying new players in colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Viktorija Sokolova, Elisabetta Crippa and Manuela Gariboldi
Funding Agency and Grant Number	Funding Agency Grant Number Associazione Italiana per la Ricerca sul Cancro 10529 Associazione Italiana per la Ricerca sul Cancro 12162
Corresponding Author	Manuela Gariboldi, PhD, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, via G. Venezian 1, 20133 Milan, Italy. manuela.gariboldi@istitutotumori.mi.it
Key Words	Colorectal cancer; Copy number variations; Gene expression; miRNA expression; Methylome; Data integration
Core Tip	The development of colorectal cancer (CRC) is driven by the accumulation of various genetic and epigenetic alterations, which have been only partially identified. The increasing financial affordability of high-throughput genome-wide assays has enabled the comprehensive analysis of genomic, transcriptomic, and epigenetic data obtained by analyzing the same biologic samples, and thereby facilitated the identification of new molecular players in CRC. An integrative approach that considers all of these multiple factors provides for better results when seeking to identify genes or microRNAs related to new interactions or biomarkers that might improve CRC diagnosis, prognosis, and treatment.
Publish Date	2016-01-06 16:13
Citation	Sokolova V, Crippa E, Gariboldi M. Integration of genome scale data for identifying new players in colorectal cancer. World J Gastroenterol 2016; 22(2): 534-545
URL	http://www.wjgnet.com/1007-9327/full/v22/i2/534.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i2.534

Full Article (PDF)	WJG-22-534.pdf
Full Article (Word)	WJG-22-534.doc
Manuscript File	20805-Review.docx
Answering Reviewers	20805-Answering reviewers.pdf
Audio Core Tip	20805-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20805-Conflict-of-interest statement.pdf
Copyright License Agreement	20805-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	20805-Language certificate.pdf
Peer-review Report	20805-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	20805-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	20805-Scientific misconduct check.pdf
Scientific Editor Work List	20805-Scientific editor work list.pdf