Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	20849
Country	United States

Received	2015-06-24 08:37
Peer-Review Started	2015-06-24 15:16
To Make the First Decision	2015-09-17 12:23
Return for Revision	2015-09-17 16:33
Revised	2015-09-19 09:17
Second Decision	2015-10-14 17:31
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-10-27 17:36
Articles in Press	2015-10-27 17:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-20 15:49
Publish the Manuscript Online	2016-01-21 14:16

ISSN	1948-9366 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Review
Article Title	Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery
Manuscript Source	Invited Manuscript
All Author List	Doris Wagner, Mara McAdams DeMarco, Neda Amini, Stefan Buttner, Dorry Segev, Faiz Gani and Timothy M Pawlik
Funding Agency and Grant Number
Corresponding Author	Timothy M Pawlik, MD, MPH, PhD, FACS, Professor, Chief, Division of Surgical Oncology, Depart­ment of Surgery, the Johns Hopkins Hospital, 600 N. Wolfe Street, Blalock 688, Baltimore, MD 21287, United States. tpawlik1@jhmi.edu
Key Words	Sarcopenia; Outcomes; Frailty; Morbidity; Mortality
Core Tip	It is estimated that by the year 2030, 36 million Americans > 65 years will require surgery. Frailty as defined by a clinically recognizable state of increased vulnerability due to physiologic stressors resulting from aging has been associated with a decreased physiologic reserve and function across multiple physi-ological systems. Recently, a loss of muscle mass or sarcopenia has been proposed as an accurate and quantitative global marker of frailty. The current review demonstrates that frailty as defined by sarcopenia can be accurately used as a preoperative predictor of poor short- and long-term postoperative outcomes following complex gastrointestinal surgery.
Publish Date	2016-01-21 14:16
Citation	Wagner D, DeMarco M, Amini N, Buttner S, Segev D, Gani F, Pawlik TM. Role of frailty and sarcopenia in predicting outcomes among patients undergoing gastrointestinal surgery. World J Gastrointest Surg 2016; 8(1): 27-40
URL	http://www.wjgnet.com/1948-9366/full/v8/i1/27.htm
DOI	http://dx.doi.org/10.4240/wjgs.v8.i1.27

Full Article (PDF)	WJGS-8-27.pdf
Full Article (Word)	WJGS-8-27.doc
Manuscript File	20849-Review.docx
Answering Reviewers	20849-Answering reviewers.pdf
Audio Core Tip	20849-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	20849-Conflict-of-interest statement.pdf
Copyright License Agreement	20849-Copyright assignment.pdf
Peer-review Report	20849-Peer-review(s).pdf
Scientific Misconduct Check	20849-Scientific misconduct check.pdf
Scientific Editor Work List	20849-Scientific editor work list.pdf