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12/23/2015 8:26:00 AM | Browse: 970 | Download: 1846
Publication Name World Journal of Transplantation
Manuscript ID 20920
Country Italy
Received
2015-06-26 09:25
Peer-Review Started
2015-06-28 10:11
To Make the First Decision
2015-08-16 17:34
Return for Revision
2015-08-26 09:12
Revised
2015-10-06 18:01
Second Decision
2015-11-09 10:58
Accepted by Journal Editor-in-Chief
2015-11-10 01:04
Accepted by Company Editor-in-Chief
2015-11-25 15:56
Articles in Press
2015-11-25 15:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-12-11 17:33
Publish the Manuscript Online
2015-12-23 08:25
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Anesthesiology
Manuscript Type Observational Study
Article Title Perioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation
Manuscript Source Invited Manuscript
All Author List Lesley De Pietri, Valentina Serra, Giuseppe Preziosi, Gianluca Rompianesi and Bruno Begliomini
Funding Agency and Grant Number
Corresponding Author Dr. Lesley De Pietri, Division of Anaes­thesiology and Intensive Care Unit, Azienda Ospedaliero- Universitaria di Modena-Policlinico, # 71 via del Pozzo, 41100 Modena, Italy. lesley.depietri@yahoo.it
Key Words Immunosuppression induction; Cytokine release; Thymoglobulin; Thromboelastography; Liver transplant
Core Tip The optimal management, in terms of dosing and timing of thymoglobulin? [antithymocyte globulin (ATG)] administration, during liver transplantation (LT) remains controversial. Several adverse effects associated with ATG infusion have been described, but the perioperative effects of ATG administration, with particular regard to coagulation and haemodynamic consequences, in patients who received a LT have never been described. Perioperative ATG administration was associated with a significantly longer surgical procedure, higher core temperature, blood loss, blood product transfusion, a higher requirement for catecholamines and continuous renal replacement therapy. The side effects and the coagulation imbalance observed in patients receiving a high dosage of ATG suggest caution in the use of thymoglobulin during LT.
Publish Date 2015-12-23 08:25
Citation De Pietri L, Serra V, Preziosi G, Rompianesi G, Begliomini B. Perioperative effects of high doses of intraoperative thymoglobulin induction in liver transplantation. World J Transplant 2015; 5(4): 320-328
URL http://www.wjgnet.com/2220-3230/full/v5/i4/320.htm
DOI http://dx.doi.org/10.5500/wjt.v5.i4.320
Full Article (PDF) WJT-5-320.pdf
Full Article (Word) WJT-5-320.doc
Manuscript File 20920-Review.docx
Answering Reviewers 20920-Answering reviewers.pdf
Audio Core Tip 20920-Audio core tip.mp3
Biostatistics Review Certificate 20920-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 20920-Conflict-of-interest statement.pdf
Copyright License Agreement 20920-Copyright assignment.pdf
Institutional Review Board Approval Form or Document 20920-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 20920-Language certificate.pdf
Peer-review Report 20920-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 20920-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 20920-Scientific misconduct check.pdf
Scientific Editor Work List 20920-Scientific editor work list .pdf