Publication Name	World Journal of Transplantation
Manuscript ID	21115
Country	United Kingdom

Received	2015-06-30 15:27
Peer-Review Started	2015-07-01 19:25
To Make the First Decision	2015-07-27 15:53
Return for Revision	2015-08-04 14:41
Revised	2015-09-10 23:17
Second Decision	2015-11-09 10:59
Accepted by Journal Editor-in-Chief	2015-11-10 00:11
Accepted by Executive Editor-in-Chief	2015-11-25 15:52
Articles in Press	2015-11-25 15:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-14 15:46
Publish the Manuscript Online	2015-12-23 08:25

ISSN	2220-3230 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Transplantation
Manuscript Type	Review
Article Title	Reducing transfusion requirements in liver transplantation
Manuscript Source	Invited Manuscript
All Author List	Ciara I Donohue and Susan V Mallett
Funding Agency and Grant Number
Corresponding Author	Ciara I Donohue, MBChB, BSc, FRCA, Anaesthetic Registrar, Royal Free Perioperative Research Group (RoFPoR), Department of Anaesthesia, Royal Free London NHS Trust, Pond Street, Hampstead, London NW3 2QG, United Kingdom. ciara.donohue@nhs.net
Key Words	Liver transplantation; Transfusion; Blood conservation; Patient blood management; Coagulation
Core Tip	Liver transplantation (LT) was historically associated with massive blood loss. Many factors have contributed to the decline in bleeding and transfusion in the past two decades including refinement of surgical techniques, anaesthetic management and the use of point of care guided goal-directed haemo-static therapies. Increasing awareness of the adverse associations of allogenic transfusion has driven the quest for transfusion-free transplantation. Increasing use of marginal grafts and transplantation of sicker recipients will continue to challenge perioperative care and transfusion practice. Inter-institutional varia-bility suggests a current lack of clear guidance and limited application of the principles of patient blood management to LT.
Publish Date	2015-12-23 08:25
Citation	Donohue CI, Mallett SV. Reducing transfusion requirements in liver transplantation. World J Transplant 2015; 5(4): 165-182
URL	http://www.wjgnet.com/2220-3230/full/v5/i4/165.htm
DOI	http://dx.doi.org/10.5500/wjt.v5.i4.165

Full Article (PDF)	WJT-5-165.pdf
Full Article (Word)	WJT-5-165.doc
Manuscript File	21115-Review.docx
Answering Reviewers	21115-Answering reviewers.pdf
Audio Core Tip	21115-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	21115-Conflict-of-interest statement.pdf
Copyright License Agreement	21115-Copyright assignment.pdf
Peer-review Report	21115-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21115-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21115-Scientific misconduct check.pdf
Scientific Editor Work List	21115-Scientific editor work list .pdf