Publication Name	World Journal of Gastroenterology
Manuscript ID	21128
Country	France

Received	2015-06-29 19:11
Peer-Review Started	2015-07-03 16:50
To Make the First Decision	2015-07-20 13:44
Return for Revision	2015-07-28 11:36
Revised	2015-08-14 23:50
Second Decision	2015-09-23 19:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-09-30 09:02
Articles in Press	2015-09-30 09:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-13 17:13
Publish the Manuscript Online	2015-10-23 15:45

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge
Manuscript Source	Invited Manuscript
All Author List	Simon Pernot, Thibault Voron, Geraldine Perkins, Christine Lagorce-Pages, Anne Berger and Julien Taieb
Funding Agency and Grant Number
Corresponding Author	Julien Taieb, Professor, Department of Gastroenterology and Digestive Oncology, Georges-Pompidou European Hospital, HEGP, 20 rue Leblanc, 75015 Paris, France. jtaieb75@gmail.com
Key Words	Gastric cancer; Signet ring cell carcinoma; Diffuse gastric cancer; hereditary diffuse gastric cancer; CDH1
Core Tip	Contrary to others gastric cancer, the incidence of signet-ring cell carcinoma (SRCC) of the stomach is rising worldwide. SRCC has a specific epidemiology and oncogenesis and has two forms: early gastric cancer, which can be resected endoscopically in some cases and which has a better outcome than non-SRCC, and advanced gastric cancer, which is generally thought to have a worse prognosis and lower chemosensitivity than non-SRCC. Its poor prognosis may be due at least in part to its more advanced stage. Therapeutic strategies are emerging but still controversial, as the benefit of perioperative chemotherapy and the value of taxane-based chemotherapy.
Publish Date	2015-10-23 15:45
Citation	Pernot S, Voron T, Perkins G, Lagorce-Pages C, Berger A, Taieb J. Signet-ring cell carcinoma of the stomach: Impact on prognosis and specific therapeutic challenge. World J Gastroenterol 2015; 21(40): 11428-11438
URL	http://www.wjgnet.com/1007-9327/full/v21/i40/11428.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i40.11428

Full Article (PDF)	WJG-21-11428.pdf
Full Article (Word)	WJG-21-11428.doc
Manuscript File	21128-Review.docx
Answering Reviewers	21128-Answering reviewers.pdf
Audio Core Tip	21128-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21128-Conflict-of-interest statement.pdf
Copyright License Agreement	21128-Copyright assessment.pdf
Non-Native Speakers of English Editing Certificate	21128-Language certificate.pdf
Peer-review Report	21128-Peer-review(s).pdf
Scientific Misconduct Check	21128-Scientific misconduct check.pdf
Scientific Editor Work List	21128-Scientific editor work list.pdf