Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	21139
Country	United States

Received	2015-06-30 13:03
Peer-Review Started	2015-07-02 22:11
To Make the First Decision	2015-07-27 15:54
Return for Revision	2015-08-04 14:58
Revised	2015-09-23 00:00
Second Decision	2015-11-02 14:22
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-11 18:08
Articles in Press	2015-11-11 18:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-21 21:35
Publish the Manuscript Online	2016-01-31 16:11

ISSN	2150-5330 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Alcoholic pancreatitis: New insights into the pathogenesis and treatment
Manuscript Source	Invited Manuscript
All Author List	Dahn L Clemens, Katrina J Schneider, Christopher K Arkfeld, Jaclyn R Grode, Mark A Wells and Shailender Singh
Funding Agency and Grant Number	Funding Agency Grant Number University of Nebraska Department of Internal Medicine, the Fred and Pamela Buffett Cancer Center, and the Nebraska Research Initiative to Clemens DL NIH to Arkfeld CK NIAAA AA020818 (to Arkfeld CK)
Corresponding Author	Dahn L Clemens, PhD, Associate Professor, Department of Internal Medicine, Section of Gastroenterology and Hepatology, University of Nebraska Medical Center, Omaha, NE 68198-8098, United States. dclemens@unmc.edu
Key Words	Alcohol; Pancreatitis; Alcoholic pancreatitis; Ethanol metabolism; Acute pancreatitis; Fatty acid ethyl esters
Core Tip	There is currently no specific pharmacotherapy for pancreatitis. Although ethanol abuse is commonly associated with both acute and chronic pancreatitis, ethanol does not itself cause pancreatitis. Instead it appears that ethanol and its metabolic by-products sensitize the pancreas to damage from other factors. Detailed understanding of the mechanisms by which ethanol sensitizes the pancreas to damage has identified a number of promising targets for therapy. It is hoped that further preclinical and clinical studies will lead to the development of successful treatment of both acute and chronic pancreatitis.
Publish Date	2016-01-31 16:11
Citation	Clemens DL, Schneider KJ, Arkfeld CK, Grode JR, Wells MA, Singh S. Alcoholic pancreatitis: New insights into the pathogenesis and treatment. World J Gastrointest Pathophysiol 2016; 7(1): 48-58
URL	http://www.wjgnet.com/2150-5330/full/v7/i1/48.htm
DOI	http://dx.doi.org/10.4291/wjgp.v7.i1.48

Full Article (PDF)	WJGP-7-48.pdf
Full Article (Word)	WJGP-7-48.doc
Manuscript File	21139-Review.docx
Answering Reviewers	21139-Answering reviewers.pdf
Audio Core Tip	21139-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21139-Conflict-of-interest statement.pdf
Copyright License Agreement	21139-Copyright assignment.pdf
Peer-review Report	21139-Peer-review(s).pdf
Scientific Misconduct Check	21139-Scientific misconduct check.pdf
Scientific Editor Work List	21139-Scientific editor work list.pdf