Publication Name	World Journal of Gastroenterology
Manuscript ID	21191
Country	United States

Received	2015-06-30 15:41
Peer-Review Started	2015-07-04 15:42
To Make the First Decision	2015-07-19 17:16
Return for Revision	2015-07-27 11:31
Revised	2015-08-11 03:08
Second Decision	2015-09-23 19:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-09-30 09:03
Articles in Press	2015-09-30 09:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-09 09:01
Publish the Manuscript Online	2015-12-24 11:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Case Report
Article Title	Rare long-term survivors of pancreatic adenocarcinoma without curative resection
Manuscript Source	Unsolicited Manuscript
All Author List	Stephen Y Oh, Alicia Edwards, Margaret T Mandelson, Bruce Lin, Russell Dorer, W Scott Helton, Richard A Kozarek and Vincent J Picozzi
Funding Agency and Grant Number
Corresponding Author	Stephen Y Oh, MD, Digestive Disease Institute, Virginia Mason Medical Center, 1100 9th Ave., MS: C3-GAS, Seattle, WA 98101, United States. oys801202@gmail.com
Key Words	Non-resected pancreatic cancer; Long-term survival; 5-year survival; Chemotherapy; Cholangitis; Second malignancy; Malnutrition
Core Tip	Five-year survival in patients with pancreatic cancer without curative resection is rare and has not been well described in the literature. At our institution from 1995 to 2009, non-resected ≥ 5-year survivors represented 2% (11/544) of all non-resected patients with pancreatic adenocarcinoma, and 11% (11/98) of ≥ 5-year survivors. These patients were mostly younger than 70 years of age, had excellent performance status and responded favorably to chemotherapy but suffered significant morbidities such as biliary sepsis. We speculate that tumor biology and host immunity play important roles on disease progression and survival.
Publish Date	2015-12-24 11:11
Citation	Oh SY, Edwards A, Mandelson MT, Lin B, Dorer R, Helton WS, Kozarek RA, Picozzi VJ. Rare long-term survivors of pancreatic adenocarcinoma without curative resection. World J Gastroenterol 2015; 21(48): 13574-13581
URL	http://www.wjgnet.com/1007-9327/full/v21/i48/13574.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i48.13574

Full Article (PDF)	WJG-21-13574.pdf
Full Article (Word)	WJG-21-13574.doc
Manuscript File	21191-Review.docx
Answering Reviewers	21191-Answering reviewers.pdf
Audio Core Tip	21191-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21191-Conflict of interest statement.pdf
Copyright License Agreement	21191-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150630043831.docx
Institutional Review Board Approval Form or Document	21191-Institutional review board statement.pdf
Peer-review Report	21191-Peer-review(s).pdf
Scientific Misconduct Check	21191-Scientific misconduct check.pdf
Scientific Editor Work List	21191-Scientific editor work list.pdf