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Articles Published Processes
3/23/2016 4:26:00 PM | Browse: 974 | Download: 1927
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Received |
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2015-07-01 08:51 |
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Peer-Review Started |
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2015-07-04 22:08 |
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To Make the First Decision |
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2015-10-15 08:13 |
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Return for Revision |
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2015-10-18 14:56 |
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Revised |
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2015-11-08 15:12 |
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Second Decision |
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2016-01-06 11:37 |
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Accepted by Journal Editor-in-Chief |
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2016-01-06 15:33 |
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Accepted by Executive Editor-in-Chief |
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2016-01-18 10:19 |
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Articles in Press |
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2016-01-18 10:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-03-03 11:00 |
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Publish the Manuscript Online |
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2016-03-23 16:22 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Control Study |
| Article Title |
Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ching-Yu Lai, Ling-Ling Hsieh, Reiping Tang, Regina M Santella, Chung Rong Chang-Chieh and Chih-Ching Yeh |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chang Gung Memorial Hospital |
CMRPD190071 |
| Chang Gung Memorial Hospital |
CMRPD190072 |
| Chang Gung Memorial Hospital |
CMRPD190073 |
| NIEHS center |
P30 ES009089 |
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| Corresponding Author |
Chih-Ching Yeh, PhD, Professor, School of Public Health, College of Public Health and Nutrition, Taipei Medical University, 250 Wu-Hsing Street, Taipei 11031,
Taiwan. ccyeh@tmu.edu.tw
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| Key Words |
APE1; OGG1; Taiwan; Colorectal cancer; polymorphisms |
| Core Tip |
The associations between base excision repair DNA polymorphisms and colorectal cancer (CRC) risk is controversial. The present study examined the effects of OGG1 and APE1 polymorphisms on the CRC risk by using a large-scale sample of 727 CRC cases and 736 healthy controls. Results demonstrated that OGG1 326Cys and APE1 148Glu alleles were significantly associated with an increased CRC risk in patients with stage Ⅲ + Ⅳ cancer (OR = 1.48) and females (OR = 1.41). Females carrying the APE1 148Glu/-656G haplotype also exhibited a 36% increased CRC risk. These findings suggest that OGG1 and APE1 polymorphisms are associated with stage- and sex-specific risk of CRC.
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| Publish Date |
2016-03-23 16:22 |
| Citation |
Lai CY, Hsieh LL, Tang R, Santella RM, Chang-Chieh CR, Yeh CC. Association between polymorphisms of APE1 and OGG1 and risk of colorectal cancer in Taiwan. World J Gastroenterol 2016; 22(12): 3372-3380 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i12/3372.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i12.3372 |
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