Publication Name	World Journal of Gastroenterology
Manuscript ID	2124
Country	China

Received	2013-01-30 09:31
Peer-Review Started	2013-01-30 15:41
To Make the First Decision	2013-03-11 15:03
Return for Revision	2013-03-13 12:29
Revised	2013-03-25 22:11
Second Decision	2013-04-09 20:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-04-10 07:25
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-04-24 22:38
Typeset the Manuscript	2013-06-05 08:46
Publish the Manuscript Online	2013-06-20 16:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Hepatocellular carcinoma: Clinical study of long-term survival and choice of treatment modalities
Manuscript Source	Invited Manuscript
All Author List	Ke-Tong Wu, Cun-Chuan Wang, Li-Gong Lu, Wei-Dong Zhang, Fu-Jun Zhang, Feng Shi and Chuan-Xing Li
Funding Agency and Grant Number	Funding Agency Grant Number Guangdong Province Natural Science Fund 10451008901006151
Corresponding Author	Chuan-Xing Li, MD, Department of Medical Imaging and Interventional Radiology, Cancer Center and State Key Laboratory of Oncology in South China, Sun Yat-sen University, 651 Dongfeng Road, East, Guangzhou 510060, Guangdong Province, China. lichuanh@mail.sysu.edu.cn
Key Words	Hepatocellular carcinoma; Surgery; Radiofrequency ablation; Transcatheter arterial chemoembolization; Statistical analysis; Clinical study
Core Tip	This manuscript was a retrospective analysis and it revealed that the long-term survival of hepatocellular carcinoma (HCC) patients was associated with the number of lesions, liver cirrhosis and Child-Pugh classification, whiletumor diameter, histological stage, and pretreatment level of serum ?-fetoprotein were not related. Conditions for long-term survival of HCC patients were: age over 50 years, no cirrhosis, a uninodular lesion, no vessel invasion, tumor-node-metastasis stage?Ⅰ?or Ⅱ, Child-Pugh classification Class A, and appropriate treatment. The best treatment modality for more than 10 years survival compared with 5 years survival were surgery alone > surgery-transcatheter arterial chemoembolization (TACE) > TACE-radiofrequency ablation (RFA) > TACE alone > surgery-TACE-RFA.
Publish Date	2013-06-20 16:34
Citation	Wu KT, Wang CC, Lu LG, Zhang WD, Zhang FJ, Shi F, Li CX. Hepatocellular carcinoma: Clinical study of long-term survival and choice of treatment modalities. World J Gastroenterol 2013; 19(23): 3649-3657
URL	http://www.wjgnet.com/1007-9327/full/v19/i23/3649.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i23.3649

Full Article (PDF)	WJG-19-3649.pdf
Manuscript File	2124-Review.doc
Answering Reviewers	2124-Answering reviewers.docx
Copyright License Agreement	2124-Copyright assignment.PDF
Non-Native Speakers of English Editing Certificate	2124-Language certificate.pdf
Peer-review Report	2124-Peer review(s).pdf
Scientific Editor Work List	2124-Scientific editor work list.doc