Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	21268
Country	Germany

Received	2015-07-03 09:01
Peer-Review Started	2015-07-09 09:22
To Make the First Decision	2015-09-16 13:56
Return for Revision	2015-09-18 17:51
Revised	2015-10-12 22:16
Second Decision	2015-11-30 09:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-11 16:18
Articles in Press	2015-12-11 16:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-29 16:03
Publish the Manuscript Online	2016-02-02 18:35

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Review
Article Title	Neoadjuvant radiotherapeutic strategies in pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Falk Roeder
Funding Agency and Grant Number
Corresponding Author	Dr. Falk Roeder, PhD, Department of Radiation Oncology, University Hospital of Munich (LMU), Marchioninistr 15, 81377 Munich, Germany. falk.roeder@med.uni-muenchen.de
Key Words	Pancreatic cancer; Neoadjuvant; Radiation therapy; Review; Radiation techniques
Core Tip	This review summarizes the current status of neoadjuvant radiation approaches for pancreatic cancer. Neoadjuvant chemoradiation for locally-advanced cases results in secondary resectability in a substantial proportion of patients with consecutively improved overall prognosis. In resectable pancreatic cancer, outstanding results in terms of response, local control and overall survival have been observed in several phaseⅠ/Ⅱ trials. Further investigation of neoadjuvant chemoradiation strategies should be performed preferentially in randomized trials and included evaluation of optimal sequencing with chemotherapy and patient selection based on molecular markers. Modern radiation techniques widen the therapeutic window and contribute to the reduction of toxicity.
Publish Date	2016-02-02 18:35
Citation	Roeder F. Neoadjuvant radiotherapeutic strategies in pancreatic cancer. World J Gastrointest Oncol 2016; 8(2): 186-197
URL	http://www.wjgnet.com/1948-5204/full/v8/i2/186.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i2.186

Full Article (PDF)	WJGO-8-186.pdf
Full Article (Word)	WJGO-8-186.doc
Manuscript File	21268-Review.doc
Answering Reviewers	21268-Answering reviewers.pdf
Audio Core Tip	21268-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21268-Conflict-of-interest statement.pdf
Copyright License Agreement	21268-Copyright assignment.pdf
Peer-review Report	21268-Peer-review(s).pdf
Scientific Misconduct Check	21268-Scientific misconduct check.pdf
Scientific Editor Work List	21268-Scientific editor work list.pdf