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12/10/2015 3:04:00 PM | Browse: 582 | Download: 783
Publication Name World Journal of Hepatology
Manuscript ID 21278
Country/Territory Italy
Received
2015-07-03 08:33
Peer-Review Started
2015-07-09 16:30
To Make the First Decision
2015-08-16 14:52
Return for Revision
2015-08-25 17:46
Revised
2015-10-15 06:05
Second Decision
2015-11-17 15:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-12-02 14:23
Articles in Press
2015-12-02 14:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-12-07 10:50
Publish the Manuscript Online
2015-12-10 15:03
ISSN 1948-5182 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Therapeutic and clinical aspects of portal vein thrombosis in patients with cirrhosis
Manuscript Source Invited Manuscript
All Author List Massimo Primignani, Giulia Tosetti and Vincenzo La Mura
Funding Agency and Grant Number
Corresponding Author Massimo Primignani, MD, PhD, U.O. Gastroenterologia ed Epatologia, IRCCS-Ca’ Granda, Ospedale Maggiore Policlinico, via F. Sforza 35, 20122 Milano, Italy. massimo.primignani@policlinico.mi.it
Key Words Portal vein thrombosis; Coagulopathy; Hypercoagulopathy; Direct acting oral anticoagulant drugs; Cirrhosis
Core Tip Impaired liver synthesis of both pro- and anticoagulants maintains a haemostatic balance in advanced liver disease, but this balance is more unstable than in healthy subjects and can be easily tipped towards thrombosis or bleeding. Portal vein thrombosis (PVT) frequently occurs in advanced stages of cirrhosis and, if occlusive or extensive, may complicate or impede liver transplant. Therefore, prevention and treatment of PVT are frequent issues in cirrhosis patients, particularly in those eligible to liver transplant. Current treatments are with low molecular weight heparin or vitamin K antagonists and should be continued until transplantation in liver candidates, whereas no consensus exists regard-ing the duration of anticoagulation in non-transplant candidates.
Publish Date 2015-12-10 15:03
Citation Primignani M, Tosetti G, La Mura V. Therapeutic and clinical aspects of portal vein thrombosis in patients with cirrhosis. World J Hepatol 2015; 7(29): 2906-2912
Url http://www.wjgnet.com/1948-5182/full/v7/i29/2906.htm
DOI http://dx.doi.org/10.4254/wjh.v7.i29.2906
Full Article (PDF) WJH-7-2906.pdf
Full Article (Word) WJH-7-2906.doc
Manuscript File 21278-Review.doc
Answering Reviewers 21278-Answering reviewers.pdf
Audio Core Tip 21278-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 21278-Conflict-of-interest statement.pdf
Copyright License Agreement 21278-Copyright assignment.pdf
Peer-review Report 21278-Peer-review(s).pdf
Scientific Misconduct Check 21278-Scientific misconduct check.pdf
Scientific Editor Work List 21278-Scientific editor work list.pdf