Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	21339
Country	Germany

Received	2015-07-07 09:03
Peer-Review Started	2015-07-08 17:30
To Make the First Decision	2015-10-08 16:07
Return for Revision	2015-10-13 14:21
Revised	2015-11-08 17:44
Second Decision	2015-12-18 11:28
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-04 16:23
Articles in Press	2016-01-04 16:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-26 09:36
Publish the Manuscript Online	2016-03-07 11:32

ISSN	1948-5204 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/ licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Review
Article Title	Primary prevention and treatment of venousthromboembolic events in patients with gastrointestinalcancers - Review
Manuscript Source	Invited Manuscript
All Author List	Hanno Riess, Piet Habbel, Anja Jühling, Marianne Sinn and Uwe Pelzer
Funding Agency and Grant Number
Corresponding Author	Dr. Hanno Riess, Professor, Department of Hematology, Oncology and Tumor Immunology, Charité University Medicine Berlin, Charitéplatz 1, 10117 Berlin, Germany. hanno.riess@charite.de
Key Words	Thromboembolism; Gastrointestinal cancer; Prophylaxis; Treatment; Anticoagulation
Core Tip	The risk for venous thrombosis and pulmonary embolism is clearly elevated in patients with gastrointestinal cancers. This risk is highest for patients with pancreatic, gastric or colorectal cancer and those receiving anti-cancer therapies. Available guidelines usually refer to thromboembolism in cancer patients without differentiating between types of cancer. Those patients with gastrointestinal cancers are more likely to present with additional problems such as hepatopathy-associated low platelet counts and/or prolonged prothrombin times. Furthermore, symptomatic or incidental thromboembolism of the visceral veins may occur more often. Identifying the risk factors for the development of venous thromboembolism and bleeding events may be helpful for correct initiation of primary pharmacological prevention and treatment of cancer-associated thromboembolism. Based on published guidelines and literature, this review will focus on prevention and treatment strategies of venous thromboembolism in patients with gastrointestinal cancers.
Publish Date	2016-03-07 11:32
Citation	Riess H, Habbel P, Jühling A, Sinn M, Pelzer U. Primary prevention and treatment of venous thromboembolic events in patients with gastrointestinal cancers - Review. World J Gastrointest Oncol 2016; 8(3): 258-270
URL	http://www.wjgnet. com/1948-5204/full/v8/i3/258.htm
DOI	http://dx.doi.org/10.4251/wjgo.v8.i3.258

Full Article (PDF)	WJGO-8-258.pdf
Full Article (Word)	WJGO-8-258.doc
Manuscript File	21339-Review.docx
Answering Reviewers	21339-Answering reviewers.pdf
Audio Core Tip	21339-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21339-Conflict-of-interest statement.pdf
Copyright License Agreement	21339-Copyright assignment.pdf
Peer-review Report	21339-Peer-review(s).pdf
Scientific Misconduct Check	21339-Scientific misconduct check.pdf
Scientific Editor Work List	21339-Scientific editor work list.pdf