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Articles Published Processes
9/16/2014 9:54:00 AM | Browse: 8547 | Download: 903
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Received |
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2013-01-31 08:26 |
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Peer-Review Started |
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2013-01-31 16:28 |
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To Make the First Decision |
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2013-02-21 20:40 |
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Return for Revision |
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2013-02-25 10:28 |
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Revised |
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2013-03-23 20:20 |
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Second Decision |
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2013-04-18 16:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-04-19 05:55 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-05-08 08:24 |
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Typeset the Manuscript |
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2013-05-20 20:29 |
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Publish the Manuscript Online |
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2013-06-04 12:34 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Autobiography |
Article Title |
Effect of endogenous insulin-like growth factor and stem cell factor on diabetic colonic dysmotility
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Manuscript Source |
Invited Manuscript |
All Author List |
Yun Wang, Xin-Yu Xu, Yu-Rong Tang, Wei-Wei Yang, Yu-Feng Yuan, Yue-Ji Ning, Yin-Juan Yu and Lin Lin |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
30971354 |
International Cooperation Project of Jiangsu Province Department of Health |
SBZ201100103 |
Graduate Innovation Foundation of Jiangsu Province, China |
CXZZ11_0704 |
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Corresponding Author |
Lin Lin, MD, PhD, Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University, 300 Guangzhou Rd, Gulou District, Nanjing 210029, Jiangsu Province, China. lin9100@yahoo.com.cn
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Key Words |
Diabetes; Gastrointestinal motility function; Insulin-like growth factor-1; Stem cell factor; Smooth muscle cell |
Core Tip |
Endogenous insulin-like growth factor (IGF)-1 levels in diabetic rat colonic tissues were decreased. Hyperglycemia may be involved in initiating this change. In colonic smooth muscle cells, IGF-1 had a direct effect on increasing stem cell factor mRNA and protein levels mediated by extracellular-signal-regulated kinase 1/2 signaling.
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Publish Date |
2013-06-04 12:34 |
Citation |
Wang Y, Xu XY, Tang YR, Yang WW, Yuan YF, Ning YJ, Yu YJ, Lin L. Effect of endogenous insulin-like growth factor and stem cell factor on diabetic colonic dysmotility. World J Gastroenterol 2013; 19(21): 3324-3331 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i21/3324.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i21.3324 |
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