Publication Name	World Journal of Diabetes
Manuscript ID	21405
Country	India

Received	2015-07-10 09:04
Peer-Review Started	2015-07-14 17:11
To Make the First Decision	2015-08-16 14:54
Return for Revision	2015-08-25 18:48
Revised	2015-09-14 17:44
Second Decision	2015-10-13 08:47
Accepted by Journal Editor-in-Chief	2015-10-14 10:02
Accepted by Executive Editor-in-Chief	2015-10-27 18:23
Articles in Press	2015-10-27 18:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-10-30 08:36
Publish the Manuscript Online	2015-11-11 10:00

ISSN	1948-9358 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Pharmacology & Pharmacy
Manuscript Type	Review
Article Title	Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity
Manuscript Source	Invited Manuscript
All Author List	Chandra Kanti Chakraborti
Funding Agency and Grant Number
Corresponding Author	Dr. Chandra Kanti Chakraborti, Professor, Kanak Manjari Institute of Pharmaceutical Sciences, Chhend, Rourkela 769015, Odisha, India. chandrakanti_12@rediffmail.com
Key Words	Obesity; Insulin; Insulin resistance; Type 2 diabetes mellitus; Adipocyte
Core Tip	The objective of this article is to establish the connection of obesity with that of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) by analyzing the recent developments in this field. The factors linking the three have been found to be some adipocytokines as well as certain other factors not of adipocyte origin. Of these, adiponectin appears to play the most beneficial role (so also leptin, peroxisome proliferator-activated receptors, apelin, etc.), while others (tumour necrosis factor-alpha, interleukin-6, resistin, retinol binding protein-4, dipeptidyl peptidase-4, plasminogen activator inhibitor-1, visfatin, free fatty acid, angiotensin Ⅱ and toll-like receptors) are harmful. Agonists and antagonists of these factors may be designed to fight against obesity, thereby achieving protection for IR and T2DM.
Publish Date	2015-11-11 10:00
Citation	Chakraborti CK. Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity. World J Diabetes 2015; 6(15): 1296-1308
URL	http://www.wjgnet.com/1948-9358/full/v6/i15/1296.htm
DOI	http://dx.doi.org/10.4239/wjd.v6.i15.1296

Full Article (PDF)	WJD-6-1296.pdf
Full Article (Word)	WJD-6-1296.doc
Manuscript File	21405-Review.doc
Answering Reviewers	21405-Answering reviewers.pdf
Audio Core Tip	21405-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21405-Conflict-of-interest statement.pdf
Copyright License Agreement	21405-Copyright assignment.pdf
Peer-review Report	21405-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21405-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21405-Scientific misconduct check.pdf
Scientific Editor Work List	21405-Scientific editor work list.pdf