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11/11/2015 10:00:00 AM | Browse: 507 | Download: 601
Publication Name World Journal of Diabetes
Manuscript ID 21405
Country of Manuscript Source India
Received
2015-07-10 09:04
Peer-Review Started
2015-07-14 17:11
To Make the First Decision
2015-08-16 14:54
Return for Revision
2015-08-25 18:48
Revised
2015-09-14 17:44
Second Decision
2015-10-13 08:47
Accepted by Journal Editor-in-Chief
2015-10-14 10:02
Accepted by Company Editor-in-Chief
2015-10-27 18:23
Articles in Press
2015-10-27 18:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2015-10-30 08:36
Publish the Manuscript Online
2015-11-11 10:00
ISSN 1948-9358 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pharmacology and Pharmacy
Manuscript Type Review
Article Title Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity
Manuscript Source Invited Manuscript
All Author List Chandra Kanti Chakraborti
Funding Agency and Grant Number
Corresponding author Dr. Chandra Kanti Chakraborti, Professor, Kanak Manjari Institute of Pharmaceutical Sciences, Chhend, Rourkela 769015, Odisha, India. chandrakanti_12@rediffmail.com
Keywords Obesity; Insulin; Insulin resistance; Type 2 diabetes mellitus; Adipocyte
Core Tip The objective of this article is to establish the connection of obesity with that of insulin resistance (IR) and type 2 diabetes mellitus (T2DM) by analyzing the recent developments in this field. The factors linking the three have been found to be some adipocytokines as well as certain other factors not of adipocyte origin. Of these, adiponectin appears to play the most beneficial role (so also leptin, peroxisome proliferator-activated receptors, apelin, etc.), while others (tumour necrosis factor-alpha, interleukin-6, resistin, retinol binding protein-4, dipeptidyl peptidase-4, plasminogen activator inhibitor-1, visfatin, free fatty acid, angiotensin Ⅱ and toll-like receptors) are harmful. Agonists and antagonists of these factors may be designed to fight against obesity, thereby achieving protection for IR and T2DM.
Publish Date 2015-11-11 10:00
Citation Chakraborti CK. Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity. World J Diabetes 2015; 6(15): 1296-1308
Url http://www.wjgnet.com/1948-9358/full/v6/i15/1296.htm
DOI http://dx.doi.org/10.4239/wjd.v6.i15.1296
Full Article (PDF) WJD-6-1296.pdf
Full Article (Word) WJD-6-1296.doc
Manuscript File 21405-Review.doc
Answering Reviewers 21405-Answering reviewers.pdf
Audio Core Tip 21405-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 21405-Conflict-of-interest statement.pdf
Copyright License Agreement 21405-Copyright assignment.pdf
Peer-review Report 21405-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 21405-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 21405-Scientific misconduct check.pdf
Scientific Editor Work List 21405-Scientific editor work list.pdf