Publication Name	World Journal of Gastroenterology
Manuscript ID	21432
Country	China

Received	2015-07-17 08:41
Peer-Review Started	2015-07-18 17:08
To Make the First Decision	2015-08-26 15:10
Return for Revision	2015-08-31 18:25
Revised	2015-09-20 21:13
Second Decision	2015-11-10 08:45
Accepted by Journal Editor-in-Chief	2015-11-11 11:40
Accepted by Company Editor-in-Chief	2015-11-19 13:27
Articles in Press	2015-11-19 13:27
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-12-02 19:14
Typeset the Manuscript	2016-01-11 17:28
Publish the Manuscript Online	2016-01-21 16:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Observational Study
Article Title	Association between serum α-L-fucosidase and non-alcoholic fatty liver disease: Cross-sectional study
Manuscript Source	Unsolicited Manuscript
All Author List	Zhen-ya Lu, Chao Cen, Zhou Shao, Xin-hua Chen, Cheng-fu Xu and You-ming Li
Funding Agency and Grant Number	Funding Agency Grant Number National Basic Research Program of China（973 Program） 2012CB524905 National Science and Technology Support Plan Project 2012BAI06B04 National Natural Science Foundation of China 81100278 National Natural Science Foundation of China 81170378 National Natural Science Foundation of China 81230012 National Natural Science Foundation of China 81270487 International Science and Technology Cooperation Projects of Zhejiang Province 2013C24010 Science Fund of Health Bureau of Zhejiang Province 2012RCA026
Corresponding Author	You-ming Li, MD, FACP, Professor, Department of Gastroenterology, the First Affiliated Hospital of Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. xiaofu@zju.edu.cn
Key Words	α-L-fucosidase; Biomarker; non-alcoholic fatty liver disease; metabolic syndrome; Cross-sectional study
Core Tip	Alpha-L-fucosidase (AFU) is a well-established marker for hepatocellular carcinoma. This study was the first attempt to investigate the relationship between AFU level and non-alcoholic fatty liver disease (NAFLD) in a large cross-sectional cohort from a southern urban Han Chinese population. It provided evidence that AFU level was significantly associated with NAFLD, and elevated AFU level was an independent risk factor for NAFLD. AFU may be a potential biomarker for the diagnosis of NAFLD.
Publish Date	2016-01-21 16:10
Citation	Lu ZY, Cen C, Shao Z, Chen XH, Xu CF, Li YM. Association between serum α-L-fucosidase and non-alcoholic fatty liver disease: Cross-sectional study. World J Gastroenterol 2016; 22(5): 1884-1890
URL	http://www.wjgnet.com/1007-9327/full/v22/i5/1884.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i5.1884

Full Article (PDF)	WJG-22-1884.pdf
Full Article (Word)	WJG-22-1884.doc
Manuscript File	21432-Review.doc
Answering Reviewers	21432-Answering reviewers.pdf
Audio Core Tip	21432-Audio core tip.mp3
Biostatistics Review Certificate	21432-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	21432-Conflict-of-interest statement.pdf
Copyright License Agreement	21432-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150716210326.pdf
Institutional Review Board Approval Form or Document	21432-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	21432-Language certificate.PDF
Peer-review Report	21432-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21432-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21432-Scientific misconduct check.pdf
Scientific Editor Work List	21432-Scientific editor work list.pdf