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1/20/2016 5:04:00 PM | Browse: 1013 | Download: 1486
Publication Name World Journal of Gastroenterology
Manuscript ID 21451
Country/Territory China
Received
2015-07-21 08:55
Peer-Review Started
2015-07-27 08:36
To Make the First Decision
2015-09-11 09:22
Return for Revision
2015-09-15 10:36
Revised
2015-09-25 09:53
Second Decision
2015-10-10 18:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2015-10-13 18:28
Articles in Press
2015-10-13 18:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2015-11-05 05:07
Typeset the Manuscript
2016-01-06 14:27
Publish the Manuscript Online
2016-01-20 16:55
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Infectious Diseases
Manuscript Type Topic Highlights
Article Title MicroRNA-mediated interactions between host and hepatitis C virus
Manuscript Source Unsolicited Manuscript
All Author List Hu Li, Jian-Dong Jiang and Zong-Gen Peng
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81321004
National Natural Science Foundation of China 81322050
National Mega-Project for “R&D for Innovative Drugs”, Ministry of Science and Technology, China 2012ZX09301-002-001
Ministry of Education of China NCET-12-0072
Corresponding Author Zong-Gen Peng, PhD, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Tiantan Xili, Beijing 100050, China. pumcpzg@126.com
Key Words MicroRNAs; Hepatitis C virus; Host-virus interaction; Biomarker; Therapeutic targets
Core Tip Hepatitis C virus (HCV) infection changes the expression of host miRNAs in vitro and in vivo, while host MicroRNAs (miRNAs) in turn regulate HCV life cycle through directly binding to HCV RNA and/or indirectly targeting cellular mRNAs. The miRNA-centered competitive viral and host RNA network displays a cross-regulation pattern between host mRNAs and HCV genome. Evidence based on the miRNA-mediated host/viral interactions suggests that specific miRNAs can serve as novel diagnostic/prognostic biomarkers in HCV-infected patients with liver diseases and therapeutic targets for development of anti-HCV agents in the future.
Publish Date 2016-01-20 16:55
Citation Li H, Jiang JD, Peng ZG. MicroRNA-mediated interactions between host and hepatitis C virus. World J Gastroenterol 2016; 22(4): 1487-1496
URL http://www.wjgnet.com/1007-9327/full/v22/i4/1487.htm
DOI http://dx.doi.org/10.3748/wjg.v22.i4.1487
Full Article (PDF) WJG-22-1487.pdf
Full Article (Word) WJG-22-1487.doc
Manuscript File 21451-Review.doc
Answering Reviewers 21451-Answering reviewers.pdf
Audio Core Tip 21451-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 21451-Conflict-of-interest statement.pdf
Copyright License Agreement 21451-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 21451-Language certificate.PDF
Peer-review Report 21451-Peer-review(s).pdf
Scientific Misconduct Check 21451-Scientific misconduct check.pdf
Scientific Editor Work List 21451-Scientific editor work list.pdf