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Articles Published Processes
1/20/2016 5:04:00 PM | Browse: 1149 | Download: 1796
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Received |
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2015-07-21 08:55 |
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Peer-Review Started |
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2015-07-27 08:36 |
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To Make the First Decision |
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2015-09-11 09:22 |
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Return for Revision |
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2015-09-15 10:36 |
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Revised |
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2015-09-25 09:53 |
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Second Decision |
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2015-10-10 18:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-10-13 18:28 |
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Articles in Press |
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2015-10-13 18:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2015-11-05 05:07 |
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Typeset the Manuscript |
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2016-01-06 14:27 |
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Publish the Manuscript Online |
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2016-01-20 16:55 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Topic Highlights |
| Article Title |
MicroRNA-mediated interactions between host and hepatitis C virus
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hu Li, Jian-Dong Jiang and Zong-Gen Peng |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81321004 |
| National Natural Science Foundation of China |
81322050 |
| National Mega-Project for “R&D for Innovative Drugs”, Ministry of Science and Technology, China |
2012ZX09301-002-001 |
| Ministry of Education of China |
NCET-12-0072 |
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| Corresponding Author |
Zong-Gen Peng, PhD, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 1 Tiantan Xili, Beijing 100050, China. pumcpzg@126.com
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| Key Words |
MicroRNAs; Hepatitis C virus; Host-virus interaction; Biomarker; Therapeutic targets |
| Core Tip |
Hepatitis C virus (HCV) infection changes the expression of host miRNAs in vitro and in vivo, while host MicroRNAs (miRNAs) in turn regulate HCV life cycle through directly binding to HCV RNA and/or indirectly targeting cellular mRNAs. The miRNA-centered competitive viral and host RNA network displays a cross-regulation pattern between host mRNAs and HCV genome. Evidence based on the miRNA-mediated host/viral interactions suggests that specific miRNAs can serve as novel diagnostic/prognostic biomarkers in HCV-infected patients with liver diseases and therapeutic targets for development of anti-HCV agents in the future.
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| Publish Date |
2016-01-20 16:55 |
| Citation |
Li H, Jiang JD, Peng ZG. MicroRNA-mediated interactions between host and hepatitis C virus. World J Gastroenterol 2016; 22(4): 1487-1496 |
| URL |
http://www.wjgnet.com/1007-9327/full/v22/i4/1487.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v22.i4.1487 |
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