Publication Name	World Journal of Gastroenterology
Manuscript ID	21468
Country	Taiwan

Received	2015-07-22 17:41
Peer-Review Started	2015-07-29 14:02
To Make the First Decision	2015-08-31 09:15
Return for Revision	2015-09-02 10:36
Revised	2015-09-15 09:54
Second Decision	2015-10-14 09:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-10-26 18:03
Articles in Press	2015-10-26 18:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2015-12-16 15:27
Publish the Manuscript Online	2015-12-31 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Shan-Ying Wu, Sheng-Hui Lan and Hsiao-Sheng Liu
Funding Agency and Grant Number	Funding Agency Grant Number Ministry of Science and Technology NSC 101-2320-B-006-025-MY3
Corresponding Author	Hsiao-Sheng Liu, PhD, Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, No. 1 University Road, Tainan 701, Taiwan. a713@mail.ncku.edu.tw
Key Words	Hepatitis B virus; Autophagy; MicroRNA; Hepatocellular carcinoma; Viral replication
Core Tip	A number of reviews have described auto-phagy and microRNAs (miRNAs) in the hepatitis B virus (HBV)-related tumorigenesis. However, few reviews have provided insights into the relationships among autophagy, miRNAs, HBV biogenesis and hepatocarcinogenesis. In this review, we describe the emerging role of autophagy and miRNAs in HBV replication and pathogenesis. Recent studies are reviewed in the following sections: (1) the mechanism by which HBV induces autophagy; (2) the effect of HBV-induced autophagy on HBV replication; (3) the relationship between autophagy and HBV in HBV-related hepatocarcinogenesis; (4) the mechanism by which miRNAs affects HBV replication; and (5) the regulation of miRNAs biogenesis by HBV.
Publish Date	2015-12-31 13:27
Citation	Wu SY, Lan SH, Liu HS. Autophagy and microRNA in hepatitis B virus-related hepatocellular carcinoma. World J Gastroenterol 2016; 22(1): 176-187
URL	http://www.wjgnet.com/1007-9327/full/v22/i1/176.htm
DOI	http://dx.doi.org/10.3748/wjg.v22.i1.176

Full Article (PDF)	WJG-22-176.pdf
Full Article (Word)	WJG-22-176.doc
Manuscript File	21468-Review.doc
Answering Reviewers	21468-Answering reviewers.pdf
Audio Core Tip	21468-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21468-Conflict-of-interest statement.pdf
Copyright License Agreement	21468-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	21468-Language certificate.pdf
Peer-review Report	21468-Peer-review(s).pdf
Scientific Misconduct Check	21468-Scientific misconduct check.pdf
Scientific Editor Work List	21468-Scientific editor work list.pdf