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Articles Published Processes
1/29/2016 11:06:00 AM | Browse: 884 | Download: 1605
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Received |
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2015-07-21 13:26 |
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Peer-Review Started |
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2015-07-30 11:25 |
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To Make the First Decision |
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2015-09-14 17:41 |
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Return for Revision |
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2015-09-15 14:30 |
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Revised |
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2015-10-09 11:53 |
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Second Decision |
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2015-11-23 17:59 |
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Accepted by Journal Editor-in-Chief |
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2015-11-23 23:22 |
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Accepted by Company Editor-in-Chief |
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2015-12-04 16:17 |
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Articles in Press |
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2015-12-04 16:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-20 10:58 |
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Publish the Manuscript Online |
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2016-01-29 11:06 |
| ISSN |
2150-5349 (online) |
| Open Access |
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Effect of electrical stimulation of the lower esophageal sphincter in gastroesophageal reflux disease patients refractory to proton pump inhibitors
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Edy Soffer, Leonardo Rodríguez, Patricia Rodriguez, Beatriz Gómez, Manoel G Neto and Michael D Crowell |
| Funding Agency and Grant Number |
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| Corresponding Author |
Edy Soffer, MD, Division of Gastroenterology, Keck School of Medicine, University of Southern California, 1510 San Pablo Street, HCC One, Los Angeles, CA 90033, United States. esoffer@usc.edu
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| Key Words |
Refractory gastroesophageal reflux disease; Gastroesophageal reflux; Electrical stimulation; Lower esophageal sphincter; Proton pump inhibitors |
| Core Tip |
Proton pump Inhibitors (PPI) are the main medical therapy for gastroesophageal reflux disease (GERD). However, 30%-40% of patients are unsatisfied with PPI therapy. Traditional antireflux surgery is effective but is associated with adverse effects and its numbers are declining, resulting in an unmet need for alternative therapies. Electrical stimulation therapy (EST) of the LES has been shown to significantly improve GERD symptoms and esophageal acid exposure in patients with GERD. The current study shows that patients who respond to PPI but are concerned about the drugs, as well as those with incomplete response to PPI respond equally to EST of the LES.
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| Publish Date |
2016-01-29 11:06 |
| Citation |
Soffer E, Rodríguez L, Rodriguez P, Gómez B, Neto MG, Crowell MD. Effect of electrical stimulation of the lower esophageal sphincter in gastroesophageal reflux disease patients refractory to proton pump inhibitors. World J Gastrointest Pharmacol Ther 2016; 7(1): 145-155 |
| URL |
http://www.wjgnet.com/2150-5349/full/v7/i1/145.htm |
| DOI |
http://dx.doi.org/10.4292/wjgpt.v7.i1.145 |
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