Publication Name	World Journal of Clinical Oncology
Manuscript ID	21679
Country	Lebanon

Received	2015-07-26 13:32
Peer-Review Started	2015-07-27 15:30
To Make the First Decision	2015-09-16 09:15
Return for Revision	2015-09-22 18:35
Revised	2015-10-04 00:00
Second Decision	2015-11-02 14:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-11-11 18:11
Articles in Press	2015-11-11 18:11
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-18 16:10
Publish the Manuscript Online	2016-01-30 17:42

ISSN	2218-4333 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Overview, prevention and management of chemotherapy extravasation
Manuscript Source	Invited Manuscript
All Author List	Firas Y Kreidieh, Hiba A Moukadem and Nagi S El Saghir
Funding Agency and Grant Number
Corresponding Author	Nagi S El Saghir, MD, FACP, Professor of Clinical Medicine, Director (Breast Center of Excellence, NK Basile Cancer Institute), Division of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, PO Box 11-0236, Riad El Solh 1107 2020, Beirut, Lebanon. nagi.saghir@aub.edu.lb
Key Words	Chemotherapy; Extravasation; Vesicant; Tissue damage; Dimethyl sulfoxide; Dexrazoxane; Antidote; Hyaluronidase
Core Tip	Chemotherapy administration carries safety concerns, which include accidental extravasation, to patients. We review and update readers and health care providers on the risks of chemotherapy extravasation, prevention and management. We present the definitions, grading, classification and guidelines related to chemotherapeutic drugs and groups. We present an update on prevention and management and antidotes, particularly dexrazoxane for anthracyclines extravasation. We present summary statements of American Society of Clinical Oncology, European Society of medical Oncology, Oncology Nursing Society and European Oncology Nursing Society guidelines. We stress the importance of education and training of the entire oncology team members who share responsibility to ensure the safe administration of chemotherapy and avoid extravasation.
Publish Date	2016-01-30 17:42
Citation	Kreidieh FY, Moukadem HA, El Saghir NS. Overview, prevention and management of chemotherapy extravasation. World J Clin Oncol 2016; 7(1): 87-97
URL	http://www.wjgnet.com/2218-4333/full/v7/i1/87.htm
DOI	http://dx.doi.org/10.5306/wjco.v7.i1.87

Full Article (PDF)	WJCO-7-87.pdf
Full Article (Word)	WJCO-7-87.doc
Manuscript File	21679-Review.docx
Answering Reviewers	21679-Answering reviewers.pdf
Audio Core Tip	21679-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	21679-Conflict-of-interest statement.pdf
Copyright License Agreement	21679-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Institutional_Review_Board_Statement_20150724224435.docx
Supplementary Material	Supplementary_Material_20150724224701.pdf
Peer-review Report	21679-Peer-review(s).pdf
Scientific Misconduct Check	21679-Scientific misconduct check.pdf
Scientific Editor Work List	21679-Scientific editor work list.pdf