Publication Name	World Journal of Gastroenterology
Manuscript ID	21720
Country	Japan

Received	2015-08-03 16:14
Peer-Review Started	2015-08-04 20:28
To Make the First Decision	2015-09-09 17:03
Return for Revision	2015-09-10 10:13
Revised	2015-09-22 22:20
Second Decision	2015-10-12 09:02
Accepted by Journal Editor-in-Chief	2015-10-14 03:28
Accepted by Executive Editor-in-Chief	2015-10-20 09:57
Articles in Press	2015-10-20 09:58
Publication Fee Transferred
Edit the Manuscript by Language Editor	2015-11-04 23:21
Typeset the Manuscript	2015-12-07 11:31
Publish the Manuscript Online	2015-12-24 11:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Retrospective Study
Article Title	Histological evaluation for chemotherapeutic responses of metastatic lymph nodes in gastric cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Osamu Kinoshita, Daisuke Ichikawa, Yusuke Ichijo, Shuhei Komatsu, Kazuma Okamoto, Mitsuo Kishimoto, Akio Yanagisawa and Eigo Otsuji
Funding Agency and Grant Number
Corresponding Author	Daisuke Ichikawa, MD, PhD, Lecturer, Department of Surgery, Division of Digestive Surgery, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kamigyo-ku, Kyoto 602-8566, Japan. ichikawa@koto.kpu-m.ac.jp
Key Words	Preoperative chemotherapy; Gastric cancer; Metastatic lymph node; Histological regression grade; Lymphadenectomy
Core Tip	Preoperative chemotherapy for gastric cancer does not provide any outstanding histological regression for regional metastatic lymph nodes, and residual metastatic lymph nodes were located irrespective of D1 and D2 region. In addition, no significant correlation was found between the clinical response of metastatic lymph nodes based on RECIST classification and histological response grading. Consequently, an appropriate D2 lymphadenectomy should routinely be performed in order to offer the chance of curative resection of advanced gastric cancer treated with preoperative chemotherapy.
Publish Date	2015-12-24 11:11
Citation	Kinoshita O, Ichikawa D, Ichijo Y, Komatsu S, Okamoto K, Kishimoto M, Yanagisawa A, Otsuji E. Histological evaluation for chemotherapeutic responses of metastatic lymph nodes in gastric cancer. World J Gastroenterol 2015; 21(48): 13500-13506
URL	http://www.wjgnet.com/1007-9327/full/v21/i48/13500.htm
DOI	http://dx.doi.org/10.3748/wjg.v21.i48.13500

Full Article (PDF)	WJG-21-13500.pdf
Full Article (Word)	WJG-21-13500.doc
Manuscript File	21720-Review.doc
Answering Reviewers	21720-Answering reviewers.pdf
Audio Core Tip	21720-Audio core tip.mp3
Biostatistics Review Certificate	21720-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	21720-Conflict-of-interest statement.pdf
Copyright License Agreement	21720-Copyright assignment.pdf
Signed Informed Consent Form(s) or Document(s)	Informed_Consent_Statement_20150803134807.pdf
Institutional Review Board Approval Form or Document	21720-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	21720-Language certificate.pdf
Peer-review Report	21720-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21720-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21720-Scientific misconduct check.pdf
Scientific Editor Work List	21720-Scientific editor work list.pdf