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Articles Published Processes
4/28/2016 4:33:00 PM | Browse: 1309 | Download: 1839
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Received |
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2015-08-13 15:17 |
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Peer-Review Started |
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2015-08-13 20:20 |
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To Make the First Decision |
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2015-11-06 11:08 |
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Return for Revision |
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2015-11-10 09:51 |
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Revised |
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2015-11-19 17:05 |
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Second Decision |
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2016-01-12 16:33 |
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Accepted by Journal Editor-in-Chief |
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2016-01-13 08:39 |
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Accepted by Executive Editor-in-Chief |
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2016-01-22 16:27 |
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Articles in Press |
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2016-01-22 16:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-04-24 17:55 |
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Publish the Manuscript Online |
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2016-04-28 16:02 |
ISSN |
2218-6204 (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Minireviews |
Article Title |
Role of microRNA in regulation of myeloma-related angiogenesis and survival
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Manuscript Source |
Invited Manuscript |
All Author List |
Michal A Rahat and Meir Preis |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Israel Cancer Association |
20150048 |
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Corresponding Author |
Michal A Rahat, DSc, Assistant Professor, Immunology Research Unit, Carmel Medical Center, 7 Michal St., Haifa 3436212, Israel. rahat_miki@clalit.org.il
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Key Words |
Multiple myeloma; MicroRNA; Angiogenesis; Proliferation; Apoptosis; Hypoxia; Vascular endothelial growth factor; Hypoxia-induce factor 1α; Macrophages; Endothelial cells |
Core Tip |
The pathogenesis of multiple myeloma (MM) requires that malignant cells remain viable and proliferate. Therefore, genes relating to the regulation of apoptosis, proliferation and angiogenesis are tightly regulated. Specifically, angiogenesis, which is driven by the interactions between the malignant cells and stroma cell surrounding them, is critical for MM progression. In this review we summarize the current knowledge about the regulation of the expression of genes related to apoptosis, proliferation and angiogenesis, through the activity of specific microRNAs.
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Publish Date |
2016-04-28 16:02 |
Citation |
Rahat MA, Preis M. Role of microRNA in regulation of myeloma-related angiogenesis and survival. World J Hematol 2016; 5(2): 51-60 |
URL |
http://www.wjgnet.com/2218-6204/full/v5/i2/51.htm |
DOI |
http://dx.doi.org/10.5315/wjh.v5.i2.51 |
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