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Articles Published Processes
2/16/2016 9:05:00 AM | Browse: 1236 | Download: 1873
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Received |
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2015-07-29 09:18 |
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Peer-Review Started |
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2015-07-29 17:05 |
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To Make the First Decision |
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2015-09-28 13:33 |
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Return for Revision |
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2015-09-29 18:57 |
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Revised |
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2015-10-20 14:02 |
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Second Decision |
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2015-12-12 17:13 |
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Accepted by Journal Editor-in-Chief |
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2015-12-14 22:18 |
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Accepted by Executive Editor-in-Chief |
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2015-12-21 11:25 |
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Articles in Press |
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2015-12-21 11:25 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-01-28 08:48 |
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Publish the Manuscript Online |
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2016-02-16 09:05 |
ISSN |
2220-315x (online) |
Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Immunology |
Manuscript Type |
Frontier |
Article Title |
Inflammatory diseases modelling in zebrafish
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Manuscript Source |
Invited Manuscript |
All Author List |
Camila Idelí Morales Fénero, Alicia Angelina Colombo Flores and Niels Olsen Saraiva Câmara |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
The National Counsel of Technological and Scientific Development |
134660/2013-7 |
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Corresponding Author |
Niels Olsen Saraiva Câmara, MD, PhD, Titular Professor, Laboratory of Transplantation Immunobiology, Department of Immunology, Institute of Biomedical Sciences IV, University of São Paulo, Cidade Universitária, São Paulo 05508-900, Brazil. niels@icb.usp.br |
Key Words |
Zebrafish; Western diseases; Inflammatory disorders; Obesity; Inflammatory bowel diseases |
Core Tip |
The western lifestyle with a high fat and carbohydrates diet, lack of physical activity and stress, is a trigger for different diseases with complex interactions between the host genetics, the metabolism, the immune system and the microbiota, as the inflammatory bo?wel disease (IBD), obesity and diabetes. The zebrafish has 70% homology with our genes, shares anatomic and physiological characteristics with mammals, and emerges as a new model for the study of metabolic and inflammatory diseases. In this review, we examine the existing genetic and induced zebrafish models of two important Western diseases with strong inflammatory component, IBD and obesity. |
Publish Date |
2016-02-16 09:05 |
Citation |
Morales Fénero CI, Colombo Flores AA, Câmara NOS. Inflammatory diseases modelling in zebrafish. World J Exp Med 2016; 6(1): 9-20 |
URL |
http://www.wjgnet.com/2220-315X/full/v6/i1/9.htm |
DOI |
http://dx.doi.org/10.5493/wjem.v6.i1.9 |
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