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3/18/2016 2:28:00 PM | Browse: 483 | Download: 574
Publication Name World Journal of Transplantation
Manuscript ID 21811
Country/Territory Germany
2015-08-14 16:40
Peer-Review Started
2015-08-15 08:02
To Make the First Decision
2015-09-28 11:30
Return for Revision
2015-10-06 09:55
2015-11-02 22:40
Second Decision
2015-12-24 17:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2016-01-07 16:25
Articles in Press
2016-01-07 16:25
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2016-02-20 21:55
Publish the Manuscript Online
2016-03-18 14:28
ISSN 2220-3230 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Review
Article Title Proteomics for rejection diagnosis in renal transplant patients: Where are we now?
Manuscript Source Invited Manuscript
All Author List Wilfried Gwinner, Jochen Metzger, Holger Husi and David Marx
Funding Agency and Grant Number
Funding Agency Grant Number
Deutsche Forschungsgemeinschaft GW 4/6-1
Corresponding author Wilfried Gwinner, MD, Department of Nephrology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany. gwinner.wilfried@mh-hannover.de
Keywords Kidney transplantation; Acute rejection; Chronic rejection; T cell-mediated rejection; Antibody-mediated rejection; Long-term outcome; Graft failure; Biopsy; Non-invasive markers; Proteome; Proteomics; Mass spectrometry; Diagnostic marker; Study design; Diagnostic trial
Core Tip Timely detection and treatment of acute and chronic rejection is important to maintain the allograft function in renal transplant patients. Allograft biopsies are unsuitable for continuous monitoring for rejection. This review summarizes the past experience with proteomic approaches to diagnose rejection non-invasively. Potential limitations and open questions in establishing proteomic markers for rejection are discussed, including ongoing trials and future challenges to this topic.
Publish Date 2016-03-18 14:28
Citation Gwinner W, Metzger J, Husi H, Marx D. Proteomics for rejection diagnosis in renal transplant patients: Where are we now? World J Transplant 2016; 6(1): 28-41
Url http://www.wjgnet.com/2220-3230/full/v6/i1/28.htm
DOI http://dx.doi.org/10.5500/wjt.v6.i1.28
Full Article (PDF) WJT-6-28.pdf
Full Article (Word) WJT-6-28.doc
Manuscript File 21811-Review.doc
Answering Reviewers 21811-Answering reviewers.pdf
Audio Core Tip 21811-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 21811-Conflict-of-interest statement.pdf
Copyright License Agreement 21811-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate Editing_Certificate_20150814143810.pdf
Supplementary Material Supplementary_Material_20150814144153.pdf
Peer-review Report 21811-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 21811-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 21811-Scientific misconduct check.pdf
Scientific Editor Work List 21811-Scientific editor work list.pdf