Publication Name	World Journal of Psychiatry
Manuscript ID	21827
Country	Taiwan

Received	2015-08-11 10:38
Peer-Review Started	2015-08-17 16:51
To Make the First Decision	2015-09-28 11:31
Return for Revision	2015-10-06 10:22
Revised	2015-10-20 08:56
Second Decision	2015-12-10 17:55
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2015-12-18 16:37
Articles in Press	2015-12-18 16:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-03-03 13:36
Publish the Manuscript Online	2016-03-16 12:23

ISSN	2220-3206 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Neurosciences
Manuscript Type	Review
Article Title	Biomarkers in schizophrenia: A focus on blood based diagnostics and theranostics
Manuscript Source	Invited Manuscript
All Author List	Chi-Yu Lai, Elizabeth Scarr, Madhara Udawela, Ian Everall, Wei J Chen and Brian Dean
Funding Agency and Grant Number	Funding Agency Grant Number National Science Council of Taiwan 102-2917-I-002-002 National Science Council of Taiwan 103-2811-B-002-107 Australian Research Council FT100100689 National Health and Medical Research Council APP1002240
Corresponding Author	Chi-Yu Lai, PhD, Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, 17 Xu-Zhou Road, Taipei 100, Taiwan. jchiyulai@gmail.com
Key Words	Schizophrenia; Peripheral blood; Biomarker; Diagnostics; Schizophrenia-associated phenotype; Treatment response; Clinical courses
Core Tip	n recent years, there has been search for blood-based biomarkers for schizophrenia (Sz) as a valid alternative. However, it must be acknowledged that Sz is a complex and heterogeneous disorder which needs to be further dissected into subtype using biomarkers. The scope of this review is to critically examine published blood-based biomarker of Sz, focusing on possible uses for diagnosis, treatment response, and their relationship with schizophrenia-associated phenotype. We suggest that a prediction model-based, Sz specific, blood oriented study design as well as standard blood collection procedures would be useful for development of Sz biomarkers.
Publish Date	2016-03-16 12:23
Citation	Lai CY, Scarr E, Udawela M, Everall I, Chen WJ, Dean B. Biomarkers in schizophrenia: A focus on blood based diagnostics and theranostics. World J Psychiatr 2016; 6(1): 102-117
URL	http://www.wjgnet.com/2220-3206/full/v6/i1/102.htm
DOI	http://dx.doi.org/10.5498/wjp.v6.i1.102

Full Article (PDF)	WJP-6-102.pdf
Full Article (Word)	WJP-6-102.doc
Manuscript File	21827-Review.doc
Answering Reviewers	21827-Answering reviewers.pdf
Audio Core Tip	21827-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21827-Conflict-of-interest statement.pdf
Copyright License Agreement	21827-Copyright assignment.pdf
Supplementary Material	21827-Supplementary material.doc
Peer-review Report	21827-Peer-review(s).pdf
Scientific Misconduct Check	21827-Scientific misconduct check.pdf
Scientific Editor Work List	21827-Scientific editor work list.pdf