Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	21830
Country	United States

Received	2015-07-29 08:21
Peer-Review Started	2015-07-29 16:11
To Make the First Decision	2015-10-08 16:54
Return for Revision	2015-10-13 17:22
Revised	2015-10-17 11:59
Second Decision	2015-11-27 16:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2015-12-08 15:23
Articles in Press	2015-12-08 15:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-26 17:24
Publish the Manuscript Online	2016-01-31 12:46

ISSN	1948-5190 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Diagnostic and therapeutic biomarkers in pancreaticobiliary malignancy
Manuscript Source	Invited Manuscript
All Author List	Domenico Viterbo, Valerie Gausman and Tamas Gonda
Funding Agency and Grant Number
Corresponding Author	Tamas Gonda, MD, Assistant Professor of Medicine, Division of Digestive and Liver Diseases, Columbia University Medical Center, 161 Fort Washington Avenue, Suite 862, New York, NY 10032, United States. tg2214@cumc.columbia.edu
Key Words	Biological markers; Pancreatic cancer; Cholangiocarcinoma; Diagnostic; Prognostic; Predictive; Brush specimens; Biopsies
Core Tip	The poor prognoses of pancreatic ductal adeno-carcinoma (PDAC) and cholangiocarcinoma (CCA) are strongly related to lack of effective screening modalities as well as few therapeutic options. Several novel biomarkers have been studied that have shown promise for early diagnosis and targeted therapy of these malignancies. These biomarkers provide a strong background for future clinical studies to screen for PDAC and CCA in the general population as well as to investigate molecularly targeted therapies.
Publish Date	2016-01-31 12:46
Citation	Viterbo D, Gausman V, Gonda T. Diagnostic and therapeutic biomarkers in pancreaticobiliary malignancy. World J Gastro­intest Endosc 2016; 8(3): 128-142
URL	http://www.wjgnet.com/1948-5190/full/v8/i3/128.htm
DOI	http://dx.doi.org/10.4253/wjge.v8.i3.128

Full Article (PDF)	WJGE-8-128.pdf
Full Article (Word)	WJGE-8-128.doc
Manuscript File	21830-Review.docx
Answering Reviewers	21830-Answering reviewers.pdf
Audio Core Tip	21830-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21830-Conflict-of-interest statement.pdf
Copyright License Agreement	21830-Copyright assignment.pdf
Peer-review Report	21830-Peer-review(s).pdf
Scientific Misconduct Check	21830-Scientific misconduct check.pdf
Scientific Editor Work List	21830-Scientific editor work list.pdf