| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
|
| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
|
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Adipokines, cytokines and body fat stores in hepatitis C virus liver steatosis
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Emilio González-Reimers, Javier López-Prieto, Geraldine Quintero-Platt, Ricardo Pelazas-González, M Remedios Alemán-Valls, Onán Pérez-Hernández, M José de-la-Vega-Prieto, M Angeles Gómez-Rodríguez, Candelaria Martín-González and Francisco Santolaria-Fernández |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Emilio González-Reimers, PhD, Servicio de Medicina Interna, Hospital Universitario de Canarias, Universidad de La Laguna, Ofra s/n, San Cristóbal de La Laguna, Tenerife, 38320 Canary Islands, Spain. egonrey@ull.es
|
| Key Words |
Resistin; Adiponectin; Insulin resistance; Proinflammatory cytokines; Leptin; Hepatitis C virus; Liver steatosis |
| Core Tip |
Pathogenesis of liver steatosis in hepatitis C virus (HCV) infection is complex and is not fully understood. For unknown reasons some patients, despite having a high body mass index (BMI), do not develop liver steatosis, whereas others with normal BMI develop intense liver fat deposition. We analyse if body fat and lean mass composition, insulin resistance and adipokine profile may help to identify patients with or without liver steatosis and its severity in treatment-na?ve HCV patients. Multivariate analysis showed that only trunk fat mass and insulin resistance were independently related to liver steatosis assessed on histomorphometrical grounds and its severity.
|
| Publish Date |
2016-01-07 12:14 |
| Citation |
González-Reimers E, López-Prieto J, Quintero-Platt G, Pelazas-González R, Alemán-Valls MR, Pérez-Hernández O, de-la-Vega-Prieto MJ, Gómez-Rodríguez MA, Martín-González C, Santolaria-Fernández F. Adipokines, cytokines and body fat stores in hepatitis C virus liver steatosis. World J Hepatol 2016; 8(1): 74-82 |
| URL |
http://www.wjgnet.com/1948-5182/full/v8/i1/74.htm |
| DOI |
http://dx.doi.org/10.4254/wjh.v8.i1.74 |
