Publication Name	World Journal of Cardiology
Manuscript ID	21847
Country	Netherlands

Received	2015-07-31 08:47
Peer-Review Started	2015-07-31 14:13
First Decision by Editorial Office Director
Return for Revision	2015-09-28 09:24
Revised	2015-10-12 18:40
Publication Fee Transferred
Second Decision by Editor	2015-12-11 12:31
Second Decision by Editor-in-Chief	2015-12-11 22:32
Final Decision by Editorial Office Director	2016-01-07 16:42
Articles in Press	2016-01-07 16:43
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-02-03 09:52
Publish the Manuscript Online	2016-02-22 10:45

ISSN	1949-8462 (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Review
Article Title	Micromanaging cardiac regeneration: Targeted delivery of microRNAs for cardiac repair and regeneration
Manuscript Source	Invited Manuscript
All Author List	Jan AAM Kamps and Guido Krenning
Funding Agency and Grant Number
Corresponding Author	Guido Krenning, PhD, Cardiovascular Regenerative Medicine, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Hanzeplein 1 (EA11), 9713GZ Groningen, The Netherlands. g.krenning@umcg.nl
Key Words	Cardiac repair; Cellular plasticity; Targeted drug delivery; MicroRNA; Reprogramming
Core Tip	Cardiac fibroblast reprogramming into cardiomyocytes holds great promise for future cardiac regenerative medicine therapies. Here, we discuss current advances in the state-of-the-art protocols for the direct reprogramming of cardiac fibroblasts into de novo cardiomyocytes in vitro and in vivo with an emphasis on microRNA-mediated reprogramming. Additionally, we discuss current advances on the state-of-the-art targeted drug delivery systems that can be employed to deliver these microRNAs to the damaged cardiac tissue.
Publish Date	2016-02-22 10:45
Citation	Kamps JAAM, Krenning G. Micromanaging cardiac regeneration: Targeted delivery of microRNAs for cardiac repair and regeneration. World J Cardiol 2016; 8(2): 163-179
URL	http://www.wjgnet.com/1949-8462/full/v8/i2/163.htm
DOI	http://dx.doi.org/10.4330/wjc.v8.i2.163

Full Article (PDF)	WJC-8-163.pdf
Full Article (Word)	WJC-8-163.doc
Manuscript File	21847-Review.docx
Answering Reviewers	21847-Answering reviewers.pdf
Audio Core Tip	21847-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21847-Conflict-of-interest statement.pdf
Copyright License Agreement	21847-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	21847-Language certificate.pdf
Peer-review Report	21847-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	21847-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	21847-Scientific misconduct check.pdf
Scientific Editor Work List	21847-Scientific editor work list.pdf