Publication Name	World Journal of Experimental Medicine
Manuscript ID	21879
Country	Italy

Received	2015-07-30 14:18
Peer-Review Started	2015-07-31 09:16
To Make the First Decision	2015-09-16 09:00
Return for Revision	2015-09-22 12:03
Revised
Second Decision	2015-12-23 16:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2016-01-07 16:46
Articles in Press	2016-01-07 16:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2016-01-28 08:48
Publish the Manuscript Online	2016-02-16 09:05

ISSN	2220-315x (online)
Open Access	This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Allergy
Manuscript Type	Review
Article Title	Hepatocellular carcinoma: Where are we?
Manuscript Source	Invited Manuscript
All Author List	Roberto Mazzanti, Umberto Arena and Renato Tassi
Funding Agency and Grant Number	Funding Agency Grant Number Fondazione Italiana per lo Studio del Fegato - Italian Liver Foundation
Corresponding Author	Roberto Mazzanti, MD, Professor, Department of Experimental and Clinical Medicine, School of Sciences of Human Health, University of Florence, Largo Brambilla 3, 50134 Firenze, Italy. roberto.mazzanti@unifi.it
Key Words	Hepatocellular carcinoma; Treatment; Liver cancer; Epidemiology; Liver transplantation; Percutaneous ethanol injection; Chemoembolization; Chemotherapy; Radiofrequency ablation
Core Tip	This review summarizes on the current state of the art of treatment of hepatocellular carcinoma (HCC). After a brief chapter on epidemiology, risk factors and biology of HCC, the review presents all possible therapeutic approaches for HCC, from the most effective such as liver transplantation to important but palliative treatments which can prolong patient survival such as different types of trans-artery-chemo-embolization and chemotherapy.
Publish Date	2016-02-16 09:05
Citation	Mazzanti R, Arena U, Tassi R. Hepatocellular carcinoma: Where are we? World J Exp Med 2016; 6(1): 21-36
URL	http://www.wjgnet.com/2220-315X/full/v6/i1/21.htm
DOI	http://dx.doi.org/10.5493/wjem.v6.i1.21

Full Article (PDF)	WJEM-6-21.pdf
Full Article (Word)	WJEM-6-21.doc
Manuscript File	21879-Review.docx
Answering Reviewers	21879-Answering reviewers.pdf
Audio Core Tip	21879-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	21879-Conflict-of-interest statement.pdf
Copyright License Agreement	21879-Copyright assignment.pdf
Peer-review Report	21879-Peer-review(s).pdf
Scientific Misconduct Check	21879-Scientific misconduct check.pdf
Scientific Editor Work List	21879-Scientific editor work list.pdf