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Articles Published Processes
3/22/2016 10:41:00 AM | Browse: 1079 | Download: 1675
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Received |
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2015-08-05 08:58 |
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Peer-Review Started |
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2015-08-06 11:30 |
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To Make the First Decision |
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2015-09-16 13:57 |
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Return for Revision |
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2015-09-21 18:50 |
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Revised |
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2015-10-05 12:11 |
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Second Decision |
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2015-11-30 09:44 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2015-12-11 16:43 |
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Articles in Press |
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2015-12-11 16:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2016-03-08 20:17 |
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Publish the Manuscript Online |
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2016-03-22 10:41 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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| Copyright |
© The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
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| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Review |
| Article Title |
Lipoprotein abnormalities in South Asians and its association with cardiovascular disease: Current state and future directions
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ozlem Bilen, Ayeesha Kamal and Salim S Virani |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| American Heart Association Beginning |
14BGIA20460366 |
| American Diabetes Association Clinical Science and Epidemiology award |
1-14-CE-44 |
| Baylor College of Medicine Center for Globalization Award |
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| Corresponding Author |
Salim S Virani, MD, PhD, Department of Medicine, Baylor College of Medicine, Health Services Research and Development (152) Michael E, DeBakey Veterans Affairs Medical Center 2002 Holcombe Blvd., Houston, TX 77030, United States. virani@bcm.edu
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| Key Words |
Dyslipidemia; South Asians; Asian Indians; Cardiovascular disease |
| Core Tip |
South Asians have a high prevalence of coro-nary heart disease (CHD) and suffer from early-onset CHD. Indeed, an important contributor is their unique lipid profile which is characterized by elevated levels of triglycerides, low levels of high-density lipoprotein (HDL) cholesterol, elevated lipoprotein(a) levels, a higher atherogenic particle burden despite comparable low-density lipoprotein cholesterol levels compared with other ethnic subgroups. HDL particles also appear to be smaller, dysfunctional, and proatherogenic. Despite the rapid expansion of the current literature with better understanding of the specific lipid abnormalities in this patient population, specific management goals and treatment thresholds do not exist for South Asians because of paucity of data. Current treatment recommendations are mostly extrapolated from Western guidelines. Lastly, large, prospective studies with outcomes data are needed to assess cardiovascular benefit associated with various lipid-lowering therapies (including combination therapy) in this patient population.
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| Publish Date |
2016-03-22 10:41 |
| Citation |
Bilen O, Kamal A, Virani SS. Lipoprotein abnormalities in South Asians and its association with cardiovascular disease: Current state and future directions. World J Cardiol 2016; 8(3): 247-257 |
| URL |
http://www.wjgnet.com/1949-8462/full/v8/i3/247.htm |
| DOI |
http://dx.doi.org/10.4330/wjc.v8.i3.247 |
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